Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CYP7B1 All Species: 8.18
Human Site: S13 Identified Species: 18
UniProt: O75881 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75881 NP_004811.1 506 58256 S13 S A A T G R F S L E R L G L P
Chimpanzee Pan troglodytes XP_001159731 506 58281 S13 S A A T G R F S L E R L G L P
Rhesus Macaque Macaca mulatta XP_001098766 558 64044 P59 Q P S T L Q A P R P S L V V G
Dog Lupus familis XP_544102 558 64067 A17 Q F S T V P S A W R T L G V L
Cat Felis silvestris
Mouse Mus musculus Q60991 507 58399 A16 A A S P G P L A L L G L L F A
Rat Rattus norvegicus Q63688 414 48208
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512397 571 66419 T13 R S H P N V N T S L F V K N C
Chicken Gallus gallus XP_418276 818 92343 H79 A P A P K A A H Q S Q P S L P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_699028 504 58566 S14 T I L L G F I S V L L L Y S F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VMT6 501 58204 T13 T F L V L V L T L L V L V Y V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O65790 500 57537 L19 L V I S Y K F L Y S K T Q R F
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 84.9 64.3 N.A. 64.8 52.7 N.A. 43.4 34.3 N.A. 42.4 N.A. 20.1 N.A. N.A. N.A.
Protein Similarity: 100 99.8 86.9 75.8 N.A. 79.4 67.5 N.A. 59.7 46 N.A. 61.8 N.A. 37.3 N.A. N.A. N.A.
P-Site Identity: 100 100 13.3 20 N.A. 26.6 0 N.A. 0 20 N.A. 20 N.A. 13.3 N.A. N.A. N.A.
P-Site Similarity: 100 100 33.3 40 N.A. 46.6 0 N.A. 20 33.3 N.A. 33.3 N.A. 26.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 20.3 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 39.5 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 19 28 28 0 0 10 19 19 0 0 0 0 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 19 0 0 0 0 0 % E
% Phe: 0 19 0 0 0 10 28 0 0 0 10 0 0 10 19 % F
% Gly: 0 0 0 0 37 0 0 0 0 0 10 0 28 0 10 % G
% His: 0 0 10 0 0 0 0 10 0 0 0 0 0 0 0 % H
% Ile: 0 10 10 0 0 0 10 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 10 10 0 0 0 0 10 0 10 0 0 % K
% Leu: 10 0 19 10 19 0 19 10 37 37 10 64 10 28 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 10 0 10 0 0 0 0 0 0 10 0 % N
% Pro: 0 19 0 28 0 19 0 10 0 10 0 10 0 0 28 % P
% Gln: 19 0 0 0 0 10 0 0 10 0 10 0 10 0 0 % Q
% Arg: 10 0 0 0 0 19 0 0 10 10 19 0 0 10 0 % R
% Ser: 19 10 28 10 0 0 10 28 10 19 10 0 10 10 0 % S
% Thr: 19 0 0 37 0 0 0 19 0 0 10 10 0 0 0 % T
% Val: 0 10 0 10 10 19 0 0 10 0 10 10 19 19 10 % V
% Trp: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 10 0 0 0 10 0 0 0 10 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _