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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CYP7B1
All Species:
22.73
Human Site:
S156
Identified Species:
50
UniProt:
O75881
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75881
NP_004811.1
506
58256
S156
S
L
D
I
L
L
E
S
M
M
Q
N
L
K
Q
Chimpanzee
Pan troglodytes
XP_001159731
506
58281
S156
S
L
D
I
L
L
E
S
M
M
Q
N
L
K
Q
Rhesus Macaque
Macaca mulatta
XP_001098766
558
64044
S209
S
L
D
I
L
L
E
S
M
M
Q
N
L
K
Q
Dog
Lupus familis
XP_544102
558
64067
T208
S
L
D
V
L
T
E
T
M
M
Q
N
L
K
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q60991
507
58399
T154
P
L
D
A
L
L
E
T
M
I
Q
E
V
K
E
Rat
Rattus norvegicus
Q63688
414
48208
I96
C
S
S
L
V
F
E
I
T
F
T
T
I
Y
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512397
571
66419
Q149
P
L
D
K
L
V
S
Q
V
M
H
S
L
Q
C
Chicken
Gallus gallus
XP_418276
818
92343
H464
P
L
E
I
I
S
D
H
M
M
K
N
L
Q
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_699028
504
58566
S143
A
L
D
P
L
T
F
S
M
M
G
N
L
Q
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VMT6
501
58204
S157
A
V
Y
P
V
S
Q
S
V
C
K
K
F
V
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O65790
500
57537
R155
E
I
L
R
M
L
T
R
L
S
R
Y
T
Q
T
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
84.9
64.3
N.A.
64.8
52.7
N.A.
43.4
34.3
N.A.
42.4
N.A.
20.1
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
86.9
75.8
N.A.
79.4
67.5
N.A.
59.7
46
N.A.
61.8
N.A.
37.3
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
80
N.A.
53.3
6.6
N.A.
33.3
40
N.A.
53.3
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
80
26.6
N.A.
60
73.3
N.A.
73.3
N.A.
53.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
10
0
0
0
0
0
0
0
0
10
0
0
0
0
10
% C
% Asp:
0
0
64
0
0
0
10
0
0
0
0
0
0
0
10
% D
% Glu:
10
0
10
0
0
0
55
0
0
0
0
10
0
0
19
% E
% Phe:
0
0
0
0
0
10
10
0
0
10
0
0
10
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
10
0
0
10
0
0
0
0
% H
% Ile:
0
10
0
37
10
0
0
10
0
10
0
0
10
0
0
% I
% Lys:
0
0
0
10
0
0
0
0
0
0
19
10
0
46
10
% K
% Leu:
0
73
10
10
64
46
0
0
10
0
0
0
64
0
0
% L
% Met:
0
0
0
0
10
0
0
0
64
64
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
55
0
0
0
% N
% Pro:
28
0
0
19
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
10
10
0
0
46
0
0
37
37
% Q
% Arg:
0
0
0
10
0
0
0
10
0
0
10
0
0
0
0
% R
% Ser:
37
10
10
0
0
19
10
46
0
10
0
10
0
0
0
% S
% Thr:
0
0
0
0
0
19
10
19
10
0
10
10
10
0
10
% T
% Val:
0
10
0
10
19
10
0
0
19
0
0
0
10
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
0
0
0
0
10
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _