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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CYP7B1
All Species:
15.76
Human Site:
T377
Identified Species:
34.67
UniProt:
O75881
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75881
NP_004811.1
506
58256
T377
R
F
V
E
E
D
L
T
L
S
S
E
T
G
D
Chimpanzee
Pan troglodytes
XP_001159731
506
58281
T377
R
F
V
E
E
D
L
T
L
S
S
E
T
G
D
Rhesus Macaque
Macaca mulatta
XP_001098766
558
64044
T429
R
F
V
E
E
D
L
T
L
S
A
E
T
G
D
Dog
Lupus familis
XP_544102
558
64067
T429
R
F
V
Q
E
D
L
T
L
H
S
E
T
Q
D
Cat
Felis silvestris
Mouse
Mus musculus
Q60991
507
58399
N375
R
E
V
Q
E
D
M
N
L
S
L
E
S
K
S
Rat
Rattus norvegicus
Q63688
414
48208
N307
V
F
P
P
M
I
H
N
D
P
E
V
F
D
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512397
571
66419
T370
R
I
I
Q
E
D
F
T
L
Q
L
E
D
G
R
Chicken
Gallus gallus
XP_418276
818
92343
V685
R
I
S
Q
E
D
F
V
L
K
L
E
G
D
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_699028
504
58566
C364
R
V
V
Q
E
D
F
C
L
R
L
D
G
Q
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VMT6
501
58204
F376
R
K
L
V
T
E
P
F
E
F
A
N
K
N
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O65790
500
57537
I379
S
P
T
D
D
M
K
I
G
G
Y
D
V
P
R
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
84.9
64.3
N.A.
64.8
52.7
N.A.
43.4
34.3
N.A.
42.4
N.A.
20.1
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
86.9
75.8
N.A.
79.4
67.5
N.A.
59.7
46
N.A.
61.8
N.A.
37.3
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
80
N.A.
46.6
6.6
N.A.
46.6
33.3
N.A.
33.3
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
86.6
N.A.
66.6
6.6
N.A.
60
40
N.A.
46.6
N.A.
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
19
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
10
73
0
0
10
0
0
19
10
19
37
% D
% Glu:
0
10
0
28
73
10
0
0
10
0
10
64
0
0
0
% E
% Phe:
0
46
0
0
0
0
28
10
0
10
0
0
10
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
10
10
0
0
19
37
10
% G
% His:
0
0
0
0
0
0
10
0
0
10
0
0
0
0
0
% H
% Ile:
0
19
10
0
0
10
0
10
0
0
0
0
0
0
0
% I
% Lys:
0
10
0
0
0
0
10
0
0
10
0
0
10
10
0
% K
% Leu:
0
0
10
0
0
0
37
0
73
0
37
0
0
0
0
% L
% Met:
0
0
0
0
10
10
10
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
19
0
0
0
10
0
10
0
% N
% Pro:
0
10
10
10
0
0
10
0
0
10
0
0
0
10
0
% P
% Gln:
0
0
0
46
0
0
0
0
0
10
0
0
0
19
10
% Q
% Arg:
82
0
0
0
0
0
0
0
0
10
0
0
0
0
28
% R
% Ser:
10
0
10
0
0
0
0
0
0
37
28
0
10
0
10
% S
% Thr:
0
0
10
0
10
0
0
46
0
0
0
0
37
0
0
% T
% Val:
10
10
55
10
0
0
0
10
0
0
0
10
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _