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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CYP7B1
All Species:
28.48
Human Site:
T427
Identified Species:
62.67
UniProt:
O75881
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75881
NP_004811.1
506
58256
T427
E
D
G
K
K
K
T
T
F
F
K
R
G
K
K
Chimpanzee
Pan troglodytes
XP_001159731
506
58281
T427
E
D
G
K
K
K
T
T
F
F
K
R
G
K
K
Rhesus Macaque
Macaca mulatta
XP_001098766
558
64044
T479
E
D
G
K
K
K
T
T
F
F
K
R
G
K
K
Dog
Lupus familis
XP_544102
558
64067
T479
E
D
G
K
K
K
T
T
F
F
K
K
G
K
R
Cat
Felis silvestris
Mouse
Mus musculus
Q60991
507
58399
T425
E
D
G
K
K
K
S
T
F
F
K
G
G
K
R
Rat
Rattus norvegicus
Q63688
414
48208
S342
K
G
G
K
K
L
K
S
Y
I
I
P
F
G
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512397
571
66419
T421
E
N
G
K
K
K
T
T
F
F
K
R
G
R
K
Chicken
Gallus gallus
XP_418276
818
92343
T736
E
N
G
K
K
K
T
T
F
Y
K
A
G
R
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_699028
504
58566
D415
K
D
G
K
E
K
T
D
F
Y
K
S
G
Q
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VMT6
501
58204
G424
E
R
F
L
E
S
N
G
G
G
M
K
S
Y
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O65790
500
57537
N416
K
F
N
P
D
R
Y
N
D
G
C
G
S
D
Y
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
84.9
64.3
N.A.
64.8
52.7
N.A.
43.4
34.3
N.A.
42.4
N.A.
20.1
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
86.9
75.8
N.A.
79.4
67.5
N.A.
59.7
46
N.A.
61.8
N.A.
37.3
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
80
20
N.A.
86.6
73.3
N.A.
60
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
40
N.A.
100
93.3
N.A.
86.6
N.A.
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% C
% Asp:
0
55
0
0
10
0
0
10
10
0
0
0
0
10
0
% D
% Glu:
73
0
0
0
19
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
10
10
0
0
0
0
0
73
55
0
0
10
0
0
% F
% Gly:
0
10
82
0
0
0
0
10
10
19
0
19
73
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
10
10
0
0
0
0
% I
% Lys:
28
0
0
82
73
73
10
0
0
0
73
19
0
46
55
% K
% Leu:
0
0
0
10
0
10
0
0
0
0
0
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% M
% Asn:
0
19
10
0
0
0
10
10
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
10
0
0
0
0
0
0
0
10
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% Q
% Arg:
0
10
0
0
0
10
0
0
0
0
0
37
0
19
28
% R
% Ser:
0
0
0
0
0
10
10
10
0
0
0
10
19
0
0
% S
% Thr:
0
0
0
0
0
0
64
64
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
0
10
19
0
0
0
10
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _