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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CYP7B1
All Species:
20.3
Human Site:
Y438
Identified Species:
44.67
UniProt:
O75881
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75881
NP_004811.1
506
58256
Y438
R
G
K
K
L
K
C
Y
L
M
P
F
G
T
G
Chimpanzee
Pan troglodytes
XP_001159731
506
58281
Y438
R
G
K
K
L
K
C
Y
L
M
P
F
G
T
G
Rhesus Macaque
Macaca mulatta
XP_001098766
558
64044
Y490
R
G
K
K
L
K
C
Y
L
M
P
F
G
T
G
Dog
Lupus familis
XP_544102
558
64067
Y490
K
G
K
R
L
K
Y
Y
L
L
P
F
G
I
G
Cat
Felis silvestris
Mouse
Mus musculus
Q60991
507
58399
Y436
G
G
K
R
L
K
T
Y
V
M
P
F
G
L
G
Rat
Rattus norvegicus
Q63688
414
48208
K353
P
F
G
L
G
T
S
K
C
P
G
R
Y
F
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512397
571
66419
F432
R
G
R
K
L
K
Y
F
L
M
P
F
G
S
G
Chicken
Gallus gallus
XP_418276
818
92343
F747
A
G
R
K
L
K
Y
F
L
M
P
F
G
S
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_699028
504
58566
Y426
S
G
Q
K
V
R
Y
Y
R
M
P
F
G
S
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VMT6
501
58204
V435
K
S
Y
R
D
R
G
V
Y
L
A
F
G
D
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O65790
500
57537
K427
G
S
D
Y
Y
V
Y
K
L
M
P
F
G
N
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
84.9
64.3
N.A.
64.8
52.7
N.A.
43.4
34.3
N.A.
42.4
N.A.
20.1
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
86.9
75.8
N.A.
79.4
67.5
N.A.
59.7
46
N.A.
61.8
N.A.
37.3
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
66.6
N.A.
66.6
0
N.A.
73.3
66.6
N.A.
53.3
N.A.
20
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
86.6
N.A.
80
0
N.A.
93.3
86.6
N.A.
80
N.A.
46.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
0
0
0
0
10
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
28
0
10
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
10
0
0
0
0
0
0
0
0
10
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
10
0
0
0
0
0
19
0
0
0
91
0
10
0
% F
% Gly:
19
73
10
0
10
0
10
0
0
0
10
0
91
0
91
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% I
% Lys:
19
0
46
55
0
64
0
19
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
10
64
0
0
0
64
19
0
0
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
73
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% N
% Pro:
10
0
0
0
0
0
0
0
0
10
82
0
0
0
0
% P
% Gln:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
37
0
19
28
0
19
0
0
10
0
0
10
0
0
0
% R
% Ser:
10
19
0
0
0
0
10
0
0
0
0
0
0
28
0
% S
% Thr:
0
0
0
0
0
10
10
0
0
0
0
0
0
28
0
% T
% Val:
0
0
0
0
10
10
0
10
10
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
10
10
0
46
55
10
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _