KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CYP7B1
All Species:
24.09
Human Site:
Y502
Identified Species:
53
UniProt:
O75881
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75881
NP_004811.1
506
58256
Y502
D
S
D
V
L
F
R
Y
K
V
K
S
_
_
_
Chimpanzee
Pan troglodytes
XP_001159731
506
58281
Y502
D
S
D
V
L
F
R
Y
K
V
K
S
_
_
_
Rhesus Macaque
Macaca mulatta
XP_001098766
558
64044
Y554
D
S
D
V
L
F
R
Y
K
V
K
S
_
_
_
Dog
Lupus familis
XP_544102
558
64067
Y554
A
S
D
V
F
F
R
Y
K
V
K
T
_
_
_
Cat
Felis silvestris
Mouse
Mus musculus
Q60991
507
58399
Y500
D
S
A
V
S
F
R
Y
K
A
K
S
W
R
S
Rat
Rattus norvegicus
Q63688
414
48208
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512397
571
66419
Y496
N
S
D
I
S
F
R
Y
R
W
K
A
S
L
A
Chicken
Gallus gallus
XP_418276
818
92343
Y811
D
T
D
I
A
F
R
Y
K
L
R
S
L
R
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_699028
504
58566
Y491
A
N
P
I
P
F
K
Y
K
T
R
K
T
L
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VMT6
501
58204
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O65790
500
57537
P491
P
L
R
A
M
C
R
P
R
P
I
M
S
K
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
84.9
64.3
N.A.
64.8
52.7
N.A.
43.4
34.3
N.A.
42.4
N.A.
20.1
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
86.9
75.8
N.A.
79.4
67.5
N.A.
59.7
46
N.A.
61.8
N.A.
37.3
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
75
N.A.
60
0
N.A.
40
46.6
N.A.
20
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
83.3
N.A.
60
0
N.A.
66.6
73.3
N.A.
46.6
N.A.
0
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
0
10
10
10
0
0
0
0
10
0
10
0
0
10
% A
% Cys:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% C
% Asp:
46
0
55
0
0
0
0
0
0
0
0
0
0
0
10
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
10
73
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
28
0
0
0
0
0
0
10
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
10
0
64
0
55
10
0
10
0
% K
% Leu:
0
10
0
0
28
0
0
0
0
10
0
0
10
19
10
% L
% Met:
0
0
0
0
10
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
10
10
0
0
0
0
0
0
0
0
0
0
0
0
10
% N
% Pro:
10
0
10
0
10
0
0
10
0
10
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
10
0
0
0
73
0
19
0
19
0
0
19
0
% R
% Ser:
0
55
0
0
19
0
0
0
0
0
0
46
19
0
10
% S
% Thr:
0
10
0
0
0
0
0
0
0
10
0
10
10
0
0
% T
% Val:
0
0
0
46
0
0
0
0
0
37
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
10
0
0
10
0
0
% W
% Tyr:
0
0
0
0
0
0
0
73
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
37
37
37
% _