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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALDH1L1
All Species:
48.79
Human Site:
S354
Identified Species:
71.56
UniProt:
O75891
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75891
NP_036322.2
902
98829
S354
F
F
K
S
G
A
A
S
V
D
V
V
R
L
V
Chimpanzee
Pan troglodytes
XP_516714
1144
124371
S593
F
F
K
S
G
A
A
S
V
D
V
V
R
L
V
Rhesus Macaque
Macaca mulatta
XP_001108084
1077
117462
S529
F
F
K
S
G
A
A
S
V
D
V
V
R
L
V
Dog
Lupus familis
XP_533713
902
98867
S354
F
F
K
S
G
A
A
S
V
D
V
V
R
L
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8R0Y6
902
98691
S354
F
F
K
S
G
A
A
S
V
D
V
V
R
L
V
Rat
Rattus norvegicus
P28037
902
99108
S354
F
F
K
S
G
A
A
S
V
D
V
V
R
L
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505782
1010
111425
S462
F
F
K
S
G
A
S
S
M
D
V
V
R
M
V
Chicken
Gallus gallus
O93344
518
56713
S28
A
S
L
H
L
L
P
S
P
T
L
N
L
E
I
Frog
Xenopus laevis
Q6GNL7
902
99964
S354
F
F
K
A
G
A
A
S
M
D
V
V
R
L
V
Zebra Danio
Brachydanio rerio
XP_001334699
903
100163
S355
F
F
K
S
G
A
A
S
M
D
V
V
R
L
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610107
913
100280
S363
F
F
A
S
G
A
G
S
M
D
V
V
R
L
V
Honey Bee
Apis mellifera
XP_623798
900
99997
D356
A
C
G
A
G
S
M
D
V
I
R
L
V
E
E
Nematode Worm
Caenorhab. elegans
NP_502054
908
99259
S362
F
F
E
S
G
A
S
S
A
D
V
T
R
L
V
Sea Urchin
Strong. purpuratus
XP_784777
884
96767
S354
F
F
K
M
G
A
G
S
M
D
V
A
R
L
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SU63
538
58570
I48
S
S
A
A
A
E
E
I
I
N
P
S
V
Q
V
Baker's Yeast
Sacchar. cerevisiae
P40047
520
56602
V30
Y
S
Q
A
P
L
R
V
P
I
T
L
P
N
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
76.4
81.6
92.2
N.A.
92.3
91.2
N.A.
66.4
31.1
77.8
76.5
N.A.
60.2
59.4
59.2
66.7
Protein Similarity:
100
77.1
83
96.6
N.A.
96.7
96.4
N.A.
78.5
41.7
89.5
88.1
N.A.
74.6
76.9
74.8
78.7
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
80
6.6
86.6
93.3
N.A.
80
13.3
73.3
73.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
20
100
100
N.A.
86.6
33.3
86.6
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
28.4
29
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
41.3
41.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
0
13
25
7
75
50
0
7
0
0
7
0
0
0
% A
% Cys:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
7
0
75
0
0
0
0
0
% D
% Glu:
0
0
7
0
0
7
7
0
0
0
0
0
0
13
7
% E
% Phe:
75
75
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
7
0
82
0
13
0
0
0
0
0
0
0
7
% G
% His:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
7
7
13
0
0
0
0
7
% I
% Lys:
0
0
63
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
7
0
7
13
0
0
0
0
7
13
7
69
0
% L
% Met:
0
0
0
7
0
0
7
0
32
0
0
0
0
7
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
7
0
7
0
7
0
% N
% Pro:
0
0
0
0
7
0
7
0
13
0
7
0
7
0
0
% P
% Gln:
0
0
7
0
0
0
0
0
0
0
0
0
0
7
0
% Q
% Arg:
0
0
0
0
0
0
7
0
0
0
7
0
75
0
0
% R
% Ser:
7
19
0
63
0
7
13
82
0
0
0
7
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
7
7
7
0
0
0
% T
% Val:
0
0
0
0
0
0
0
7
44
0
75
63
13
0
82
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _