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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ALDH1L1 All Species: 37.88
Human Site: S638 Identified Species: 55.56
UniProt: O75891 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75891 NP_036322.2 902 98829 S638 S L V G Q R L S D H P D V R K
Chimpanzee Pan troglodytes XP_516714 1144 124371 S880 G S A N N R L S H H P D L R K
Rhesus Macaque Macaca mulatta XP_001108084 1077 117462 S813 S L I G Q R L S D H P D V R K
Dog Lupus familis XP_533713 902 98867 S638 S L V G Q R L S D H P D V R K
Cat Felis silvestris
Mouse Mus musculus Q8R0Y6 902 98691 S638 S L V G Q R L S D H P D V R K
Rat Rattus norvegicus P28037 902 99108 S638 S L V G Q R L S D H P D V R K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505782 1010 111425 S746 G L A G Q R L S E H P D I R K
Chicken Gallus gallus O93344 518 56713 L280 E A A G R S N L K R V T L E L
Frog Xenopus laevis Q6GNL7 902 99964 S638 S L I G Q R L S D H P D V R K
Zebra Danio Brachydanio rerio XP_001334699 903 100163 S639 S L V G Q R L S D H P D V R K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610107 913 100280 A648 S D A G Q A V A D H E L V R K
Honey Bee Apis mellifera XP_623798 900 99997 C636 T E T G N A I C E H L L I R K
Nematode Worm Caenorhab. elegans NP_502054 908 99259 T644 S L V G N R L T A H P D V R K
Sea Urchin Strong. purpuratus XP_784777 884 96767 A636 S V C G Q R M A D H P D V R K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SU63 538 58570 K300 L A A N S N L K P V T L E L G
Baker's Yeast Sacchar. cerevisiae P40047 520 56602 V282 M K V A A D T V K K V T L E L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 76.4 81.6 92.2 N.A. 92.3 91.2 N.A. 66.4 31.1 77.8 76.5 N.A. 60.2 59.4 59.2 66.7
Protein Similarity: 100 77.1 83 96.6 N.A. 96.7 96.4 N.A. 78.5 41.7 89.5 88.1 N.A. 74.6 76.9 74.8 78.7
P-Site Identity: 100 53.3 93.3 100 N.A. 100 100 N.A. 73.3 6.6 93.3 100 N.A. 53.3 26.6 80 73.3
P-Site Similarity: 100 60 100 100 N.A. 100 100 N.A. 86.6 20 100 100 N.A. 66.6 53.3 86.6 93.3
Percent
Protein Identity: N.A. N.A. N.A. 28.4 29 N.A.
Protein Similarity: N.A. N.A. N.A. 41.3 41.8 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 6.6 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 13 32 7 7 13 0 13 7 0 0 0 0 0 0 % A
% Cys: 0 0 7 0 0 0 0 7 0 0 0 0 0 0 0 % C
% Asp: 0 7 0 0 0 7 0 0 57 0 0 69 0 0 0 % D
% Glu: 7 7 0 0 0 0 0 0 13 0 7 0 7 13 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 13 0 0 82 0 0 0 0 0 0 0 0 0 0 7 % G
% His: 0 0 0 0 0 0 0 0 7 82 0 0 0 0 0 % H
% Ile: 0 0 13 0 0 0 7 0 0 0 0 0 13 0 0 % I
% Lys: 0 7 0 0 0 0 0 7 13 7 0 0 0 0 82 % K
% Leu: 7 57 0 0 0 0 69 7 0 0 7 19 19 7 13 % L
% Met: 7 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 13 19 7 7 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 7 0 69 0 0 0 0 % P
% Gln: 0 0 0 0 63 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 7 69 0 0 0 7 0 0 0 82 0 % R
% Ser: 63 7 0 0 7 7 0 57 0 0 0 0 0 0 0 % S
% Thr: 7 0 7 0 0 0 7 7 0 0 7 13 0 0 0 % T
% Val: 0 7 44 0 0 0 7 7 0 7 13 0 63 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _