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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ALDH1L1 All Species: 43.64
Human Site: T159 Identified Species: 64
UniProt: O75891 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75891 NP_036322.2 902 98829 T159 C E V L P D D T V S T L Y N R
Chimpanzee Pan troglodytes XP_516714 1144 124371 T398 C E V L P D D T V S T L Y N R
Rhesus Macaque Macaca mulatta XP_001108084 1077 117462 T332 C E V L P D D T V S T L Y N R
Dog Lupus familis XP_533713 902 98867 T159 C E I L P D D T V S T L Y N R
Cat Felis silvestris
Mouse Mus musculus Q8R0Y6 902 98691 T159 C D V L P D D T V S T L Y N R
Rat Rattus norvegicus P28037 902 99108 T159 C E V L P D D T V S T L Y N R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505782 1010 111425 T268 C A V E P N D T V D V L Y N R
Chicken Gallus gallus O93344 518 56713
Frog Xenopus laevis Q6GNL7 902 99964 T159 C E V L P D D T V N T I Y N R
Zebra Danio Brachydanio rerio XP_001334699 903 100163 N159 C D V E P N D N V N S I Y K R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610107 913 100280 T164 T N V E S T D T L D T I Y K R
Honey Bee Apis mellifera XP_623798 900 99997 T162 C K V N S N D T L D S L Y N N
Nematode Worm Caenorhab. elegans NP_502054 908 99259 T165 C K V E E N D T L N T L Y K R
Sea Urchin Strong. purpuratus XP_784777 884 96767 T159 V D V D P N E T V D T L Y N R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SU63 538 58570
Baker's Yeast Sacchar. cerevisiae P40047 520 56602
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 76.4 81.6 92.2 N.A. 92.3 91.2 N.A. 66.4 31.1 77.8 76.5 N.A. 60.2 59.4 59.2 66.7
Protein Similarity: 100 77.1 83 96.6 N.A. 96.7 96.4 N.A. 78.5 41.7 89.5 88.1 N.A. 74.6 76.9 74.8 78.7
P-Site Identity: 100 100 100 93.3 N.A. 93.3 100 N.A. 66.6 0 86.6 46.6 N.A. 40 46.6 53.3 60
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 73.3 0 100 80 N.A. 53.3 73.3 80 80
Percent
Protein Identity: N.A. N.A. N.A. 28.4 29 N.A.
Protein Similarity: N.A. N.A. N.A. 41.3 41.8 N.A.
P-Site Identity: N.A. N.A. N.A. 0 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 0 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 69 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 19 0 7 0 44 75 0 0 25 0 0 0 0 0 % D
% Glu: 0 38 0 25 7 0 7 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 7 0 0 0 0 0 0 0 0 19 0 0 0 % I
% Lys: 0 13 0 0 0 0 0 0 0 0 0 0 0 19 0 % K
% Leu: 0 0 0 44 0 0 0 0 19 0 0 63 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 7 0 7 0 32 0 7 0 19 0 0 0 63 7 % N
% Pro: 0 0 0 0 63 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 75 % R
% Ser: 0 0 0 0 13 0 0 0 0 38 13 0 0 0 0 % S
% Thr: 7 0 0 0 0 7 0 75 0 0 63 0 0 0 0 % T
% Val: 7 0 75 0 0 0 0 0 63 0 7 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 82 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _