KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALDH1L1
All Species:
54.55
Human Site:
T649
Identified Species:
80
UniProt:
O75891
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75891
NP_036322.2
902
98829
T649
D
V
R
K
I
G
F
T
G
S
T
E
V
G
K
Chimpanzee
Pan troglodytes
XP_516714
1144
124371
T891
D
L
R
K
I
G
F
T
G
S
T
E
V
G
K
Rhesus Macaque
Macaca mulatta
XP_001108084
1077
117462
T824
D
V
R
K
I
G
F
T
G
S
T
E
V
G
K
Dog
Lupus familis
XP_533713
902
98867
T649
D
V
R
K
I
G
F
T
G
S
T
E
V
G
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8R0Y6
902
98691
T649
D
V
R
K
I
G
F
T
G
S
T
E
V
G
K
Rat
Rattus norvegicus
P28037
902
99108
T649
D
V
R
K
I
G
F
T
G
S
T
E
V
G
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505782
1010
111425
T757
D
I
R
K
L
G
F
T
G
S
T
P
I
G
K
Chicken
Gallus gallus
O93344
518
56713
S291
T
L
E
L
G
G
K
S
P
N
I
I
F
A
D
Frog
Xenopus laevis
Q6GNL7
902
99964
T649
D
V
R
K
I
G
F
T
G
S
T
P
I
G
K
Zebra Danio
Brachydanio rerio
XP_001334699
903
100163
T650
D
V
R
K
L
G
F
T
G
S
T
E
I
G
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610107
913
100280
T659
L
V
R
K
L
G
F
T
G
S
T
P
I
G
K
Honey Bee
Apis mellifera
XP_623798
900
99997
T647
L
I
R
K
L
G
F
T
G
S
T
Q
I
G
Q
Nematode Worm
Caenorhab. elegans
NP_502054
908
99259
T655
D
V
R
K
I
G
F
T
G
S
T
E
I
G
A
Sea Urchin
Strong. purpuratus
XP_784777
884
96767
T647
D
V
R
K
L
G
F
T
G
S
T
P
I
G
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SU63
538
58570
P311
L
E
L
G
G
K
S
P
F
I
V
F
E
D
A
Baker's Yeast
Sacchar. cerevisiae
P40047
520
56602
S293
T
L
E
L
G
G
K
S
P
N
I
V
F
A
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
76.4
81.6
92.2
N.A.
92.3
91.2
N.A.
66.4
31.1
77.8
76.5
N.A.
60.2
59.4
59.2
66.7
Protein Similarity:
100
77.1
83
96.6
N.A.
96.7
96.4
N.A.
78.5
41.7
89.5
88.1
N.A.
74.6
76.9
74.8
78.7
P-Site Identity:
100
93.3
100
100
N.A.
100
100
N.A.
73.3
6.6
86.6
86.6
N.A.
73.3
60
86.6
73.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
93.3
26.6
93.3
100
N.A.
86.6
93.3
93.3
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
28.4
29
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
41.3
41.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
13
13
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
69
0
0
0
0
0
0
0
0
0
0
0
0
7
13
% D
% Glu:
0
7
13
0
0
0
0
0
0
0
0
50
7
0
0
% E
% Phe:
0
0
0
0
0
0
82
0
7
0
0
7
13
0
0
% F
% Gly:
0
0
0
7
19
94
0
0
82
0
0
0
0
82
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
13
0
0
50
0
0
0
0
7
13
7
44
0
0
% I
% Lys:
0
0
0
82
0
7
13
0
0
0
0
0
0
0
63
% K
% Leu:
19
19
7
13
32
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% M
% Asn:
0
0
0
0
0
0
0
0
0
13
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
7
13
0
0
25
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
7
% Q
% Arg:
0
0
82
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
7
13
0
82
0
0
0
0
0
% S
% Thr:
13
0
0
0
0
0
0
82
0
0
82
0
0
0
0
% T
% Val:
0
63
0
0
0
0
0
0
0
0
7
7
38
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _