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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ALDH1L1 All Species: 50.91
Human Site: Y164 Identified Species: 74.67
UniProt: O75891 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75891 NP_036322.2 902 98829 Y164 D D T V S T L Y N R F L F P E
Chimpanzee Pan troglodytes XP_516714 1144 124371 Y403 D D T V S T L Y N R F L F P E
Rhesus Macaque Macaca mulatta XP_001108084 1077 117462 Y337 D D T V S T L Y N R F L F P E
Dog Lupus familis XP_533713 902 98867 Y164 D D T V S T L Y N R F L F P E
Cat Felis silvestris
Mouse Mus musculus Q8R0Y6 902 98691 Y164 D D T V S T L Y N R F L F P E
Rat Rattus norvegicus P28037 902 99108 Y164 D D T V S T L Y N R F L F P E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505782 1010 111425 Y273 N D T V D V L Y N R F L F P E
Chicken Gallus gallus O93344 518 56713
Frog Xenopus laevis Q6GNL7 902 99964 Y164 D D T V N T I Y N R F L F P E
Zebra Danio Brachydanio rerio XP_001334699 903 100163 Y164 N D N V N S I Y K R F L F P E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610107 913 100280 Y169 T D T L D T I Y K R F L Y P E
Honey Bee Apis mellifera XP_623798 900 99997 Y167 N D T L D S L Y N N F L Y P E
Nematode Worm Caenorhab. elegans NP_502054 908 99259 Y170 N D T L N T L Y K R F L Y P A
Sea Urchin Strong. purpuratus XP_784777 884 96767 Y164 N E T V D T L Y N R F L Y P E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SU63 538 58570
Baker's Yeast Sacchar. cerevisiae P40047 520 56602
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 76.4 81.6 92.2 N.A. 92.3 91.2 N.A. 66.4 31.1 77.8 76.5 N.A. 60.2 59.4 59.2 66.7
Protein Similarity: 100 77.1 83 96.6 N.A. 96.7 96.4 N.A. 78.5 41.7 89.5 88.1 N.A. 74.6 76.9 74.8 78.7
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 80 0 86.6 60 N.A. 60 60 60 73.3
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 86.6 0 100 86.6 N.A. 80 86.6 86.6 93.3
Percent
Protein Identity: N.A. N.A. N.A. 28.4 29 N.A.
Protein Similarity: N.A. N.A. N.A. 41.3 41.8 N.A.
P-Site Identity: N.A. N.A. N.A. 0 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 0 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 44 75 0 0 25 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 75 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 82 0 57 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 19 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 19 0 0 0 0 0 0 % K
% Leu: 0 0 0 19 0 0 63 0 0 0 0 82 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 32 0 7 0 19 0 0 0 63 7 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 82 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 75 0 0 0 0 0 % R
% Ser: 0 0 0 0 38 13 0 0 0 0 0 0 0 0 0 % S
% Thr: 7 0 75 0 0 63 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 63 0 7 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 82 0 0 0 0 25 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _