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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALDH1L1
All Species:
28.48
Human Site:
Y408
Identified Species:
41.78
UniProt:
O75891
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75891
NP_036322.2
902
98829
Y408
E
G
E
C
S
I
D
Y
V
E
M
A
V
N
K
Chimpanzee
Pan troglodytes
XP_516714
1144
124371
Y647
E
G
E
C
S
I
D
Y
V
E
M
A
V
N
K
Rhesus Macaque
Macaca mulatta
XP_001108084
1077
117462
Y583
E
G
E
C
S
I
D
Y
V
E
M
A
V
N
K
Dog
Lupus familis
XP_533713
902
98867
Y408
A
S
E
C
I
I
D
Y
V
E
K
A
V
N
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8R0Y6
902
98691
Y408
E
S
E
C
V
I
N
Y
V
E
K
A
V
K
K
Rat
Rattus norvegicus
P28037
902
99108
Y408
E
S
E
C
V
I
N
Y
V
E
R
A
V
N
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505782
1010
111425
Y516
E
E
E
L
V
V
D
Y
V
S
K
E
I
N
N
Chicken
Gallus gallus
O93344
518
56713
Q65
Y
N
P
A
T
G
E
Q
I
C
E
I
Q
E
A
Frog
Xenopus laevis
Q6GNL7
902
99964
Y408
E
E
E
L
V
I
D
Y
V
E
K
E
I
N
N
Zebra Danio
Brachydanio rerio
XP_001334699
903
100163
Y409
E
E
E
F
N
V
D
Y
V
E
K
K
L
N
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610107
913
100280
A419
N
Q
Q
L
D
F
E
A
F
T
L
K
A
N
K
Honey Bee
Apis mellifera
XP_623798
900
99997
A407
S
K
E
I
K
Y
D
A
V
E
V
Q
T
N
N
Nematode Worm
Caenorhab. elegans
NP_502054
908
99259
P414
G
I
S
V
T
Y
D
P
I
V
L
N
V
N
N
Sea Urchin
Strong. purpuratus
XP_784777
884
96767
A406
E
Q
V
F
E
F
D
A
F
E
M
H
V
N
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SU63
538
58570
V85
L
D
P
R
T
G
E
V
I
A
H
V
A
E
G
Baker's Yeast
Sacchar. cerevisiae
P40047
520
56602
S67
T
F
D
V
I
N
P
S
N
E
E
K
I
T
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
76.4
81.6
92.2
N.A.
92.3
91.2
N.A.
66.4
31.1
77.8
76.5
N.A.
60.2
59.4
59.2
66.7
Protein Similarity:
100
77.1
83
96.6
N.A.
96.7
96.4
N.A.
78.5
41.7
89.5
88.1
N.A.
74.6
76.9
74.8
78.7
P-Site Identity:
100
100
100
73.3
N.A.
66.6
73.3
N.A.
40
0
53.3
46.6
N.A.
13.3
33.3
20
40
P-Site Similarity:
100
100
100
73.3
N.A.
73.3
80
N.A.
53.3
20
60
66.6
N.A.
33.3
40
40
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
28.4
29
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
41.3
41.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
7
0
0
0
19
0
7
0
38
13
0
7
% A
% Cys:
0
0
0
38
0
0
0
0
0
7
0
0
0
0
0
% C
% Asp:
0
7
7
0
7
0
63
0
0
0
0
0
0
0
0
% D
% Glu:
57
19
63
0
7
0
19
0
0
69
13
13
0
13
0
% E
% Phe:
0
7
0
13
0
13
0
0
13
0
0
0
0
0
0
% F
% Gly:
7
19
0
0
0
13
0
0
0
0
0
0
0
0
7
% G
% His:
0
0
0
0
0
0
0
0
0
0
7
7
0
0
0
% H
% Ile:
0
7
0
7
13
44
0
0
19
0
0
7
19
0
0
% I
% Lys:
0
7
0
0
7
0
0
0
0
0
32
19
0
7
44
% K
% Leu:
7
0
0
19
0
0
0
0
0
0
13
0
7
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
25
0
0
0
0
% M
% Asn:
7
7
0
0
7
7
13
0
7
0
0
7
0
75
38
% N
% Pro:
0
0
13
0
0
0
7
7
0
0
0
0
0
0
0
% P
% Gln:
0
13
7
0
0
0
0
7
0
0
0
7
7
0
0
% Q
% Arg:
0
0
0
7
0
0
0
0
0
0
7
0
0
0
0
% R
% Ser:
7
19
7
0
19
0
0
7
0
7
0
0
0
0
0
% S
% Thr:
7
0
0
0
19
0
0
0
0
7
0
0
7
7
7
% T
% Val:
0
0
7
13
25
13
0
7
63
7
7
7
50
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
0
13
0
57
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _