KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TUSC2
All Species:
27.62
Human Site:
S6
Identified Species:
60.77
UniProt:
O75896
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75896
NP_009206.1
110
12074
S6
_
_
M
G
A
S
G
S
K
A
R
G
L
W
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001101682
110
12015
S6
_
_
M
G
A
S
G
S
K
A
R
G
L
W
P
Dog
Lupus familis
XP_850728
75
8685
Cat
Felis silvestris
Mouse
Mus musculus
Q9WVF8
110
12117
S6
_
_
M
G
A
S
G
S
K
A
R
G
L
W
P
Rat
Rattus norvegicus
NP_001102767
110
12105
S6
_
_
M
G
A
S
G
S
K
A
R
G
L
W
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508436
114
12425
S6
_
_
M
G
T
S
G
S
K
S
R
G
L
W
P
Chicken
Gallus gallus
XP_414259
60
7099
Frog
Xenopus laevis
NP_001083429
106
12052
S6
_
_
M
G
G
S
A
S
K
A
R
G
L
W
P
Zebra Danio
Brachydanio rerio
NP_001070767
111
12170
S6
_
_
M
G
G
S
G
S
K
P
K
G
V
W
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q93196
123
14219
S6
_
_
M
G
L
G
S
S
K
R
K
E
E
P
P
Sea Urchin
Strong. purpuratus
XP_799314
123
13644
F8
M
G
G
K
S
S
S
F
M
Q
K
V
V
S
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99
61.8
N.A.
92.7
93.6
N.A.
78.9
48.1
62.7
70.2
N.A.
N.A.
N.A.
33.3
37.4
Protein Similarity:
100
N.A.
99
61.8
N.A.
94.5
94.5
N.A.
90.3
53.6
80
83.7
N.A.
N.A.
N.A.
53.6
54.4
P-Site Identity:
100
N.A.
100
0
N.A.
100
100
N.A.
84.6
0
84.6
69.2
N.A.
N.A.
N.A.
38.4
13.3
P-Site Similarity:
100
N.A.
100
0
N.A.
100
100
N.A.
92.3
0
84.6
84.6
N.A.
N.A.
N.A.
46.1
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
37
0
10
0
0
46
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
10
10
0
0
% E
% Phe:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% F
% Gly:
0
10
10
73
19
10
55
0
0
0
0
64
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
10
0
0
0
0
73
0
28
0
0
0
0
% K
% Leu:
0
0
0
0
10
0
0
0
0
0
0
0
55
0
0
% L
% Met:
10
0
73
0
0
0
0
0
10
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
10
0
0
0
10
82
% P
% Gln:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
10
55
0
0
0
0
% R
% Ser:
0
0
0
0
10
73
19
73
0
10
0
0
0
10
0
% S
% Thr:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
10
19
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
64
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
73
73
0
0
0
0
0
0
0
0
0
0
0
0
0
% _