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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TUSC2
All Species:
13.64
Human Site:
Y53
Identified Species:
30
UniProt:
O75896
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75896
NP_009206.1
110
12074
Y53
T
R
R
G
S
M
F
Y
D
E
D
G
D
L
A
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001101682
110
12015
Y53
T
R
R
G
S
M
F
Y
D
E
D
G
D
L
A
Dog
Lupus familis
XP_850728
75
8685
A42
T
K
N
G
Q
K
R
A
K
L
R
R
V
H
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9WVF8
110
12117
Y53
T
R
R
G
S
M
F
Y
D
E
D
G
D
L
A
Rat
Rattus norvegicus
NP_001102767
110
12105
Y53
T
R
R
G
S
M
F
Y
D
E
D
G
D
L
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508436
114
12425
F57
T
R
R
G
S
M
Y
F
D
E
D
G
D
L
A
Chicken
Gallus gallus
XP_414259
60
7099
K25
I
V
T
K
N
G
R
K
R
A
K
L
K
R
I
Frog
Xenopus laevis
NP_001083429
106
12052
F49
T
R
R
G
S
M
Y
F
D
E
D
G
D
L
A
Zebra Danio
Brachydanio rerio
NP_001070767
111
12170
F54
T
R
R
S
S
L
Y
F
D
E
D
G
D
L
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q93196
123
14219
I63
E
A
K
S
S
Q
Y
I
D
E
D
G
D
V
A
Sea Urchin
Strong. purpuratus
XP_799314
123
13644
F63
T
R
T
S
S
M
Y
F
D
E
D
G
Q
V
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99
61.8
N.A.
92.7
93.6
N.A.
78.9
48.1
62.7
70.2
N.A.
N.A.
N.A.
33.3
37.4
Protein Similarity:
100
N.A.
99
61.8
N.A.
94.5
94.5
N.A.
90.3
53.6
80
83.7
N.A.
N.A.
N.A.
53.6
54.4
P-Site Identity:
100
N.A.
100
13.3
N.A.
100
100
N.A.
86.6
0
86.6
73.3
N.A.
N.A.
N.A.
46.6
60
P-Site Similarity:
100
N.A.
100
20
N.A.
100
100
N.A.
100
6.6
100
93.3
N.A.
N.A.
N.A.
66.6
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
0
10
0
10
0
0
0
0
82
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
82
0
82
0
73
0
0
% D
% Glu:
10
0
0
0
0
0
0
0
0
82
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
37
37
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
64
0
10
0
0
0
0
0
82
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% H
% Ile:
10
0
0
0
0
0
0
10
0
0
0
0
0
0
10
% I
% Lys:
0
10
10
10
0
10
0
10
10
0
10
0
10
0
10
% K
% Leu:
0
0
0
0
0
10
0
0
0
10
0
10
0
64
0
% L
% Met:
0
0
0
0
0
64
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
10
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
10
10
0
0
0
0
0
0
10
0
0
% Q
% Arg:
0
73
64
0
0
0
19
0
10
0
10
10
0
10
0
% R
% Ser:
0
0
0
28
82
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
82
0
19
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
10
0
0
0
0
0
0
0
0
0
0
10
19
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
46
37
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _