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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DGAT1
All Species:
28.18
Human Site:
S270
Identified Species:
56.36
UniProt:
O75907
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75907
NP_036211.2
488
55278
S270
Y
E
L
N
F
P
R
S
P
R
I
R
K
R
F
Chimpanzee
Pan troglodytes
XP_520014
488
54742
S270
Y
E
L
N
F
P
R
S
P
R
I
R
K
R
F
Rhesus Macaque
Macaca mulatta
XP_001090134
491
55617
S273
Y
E
L
N
F
P
R
S
P
R
I
R
K
R
F
Dog
Lupus familis
XP_849176
498
56652
F267
R
D
L
Y
Y
F
L
F
A
P
T
L
C
Y
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2A7
498
56772
P279
L
C
Y
E
L
N
F
P
R
S
P
R
I
R
K
Rat
Rattus norvegicus
Q9ERM3
498
56852
P279
L
C
Y
E
L
N
F
P
R
S
P
R
I
R
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_956024
499
57133
L270
Y
F
A
F
A
P
T
L
C
Y
E
L
N
F
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609813
565
64925
T340
Y
E
L
N
F
P
R
T
S
R
V
R
K
R
F
Honey Bee
Apis mellifera
XP_624754
498
58148
T273
Y
E
L
N
F
P
R
T
Q
R
I
R
K
R
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780515
485
56246
T264
Y
E
L
N
F
P
R
T
K
R
I
R
K
R
F
Poplar Tree
Populus trichocarpa
XP_002330510
493
56790
S273
Y
Q
S
S
Y
P
R
S
A
S
V
R
K
G
W
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53629
642
74004
T427
Y
Q
I
E
Y
P
R
T
K
E
I
R
W
S
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.2
96.3
86.5
N.A.
84.7
84.7
N.A.
N.A.
N.A.
N.A.
62.5
N.A.
37.1
35.9
N.A.
35.8
Protein Similarity:
100
96.3
97.5
89.7
N.A.
90.3
90.3
N.A.
N.A.
N.A.
N.A.
74.5
N.A.
55.2
52
N.A.
53.2
P-Site Identity:
100
100
100
6.6
N.A.
13.3
13.3
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
80
86.6
N.A.
86.6
P-Site Similarity:
100
100
100
20
N.A.
13.3
13.3
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
93.3
93.3
N.A.
93.3
Percent
Protein Identity:
36.1
N.A.
N.A.
N.A.
23.2
N.A.
Protein Similarity:
54.9
N.A.
N.A.
N.A.
41.4
N.A.
P-Site Identity:
40
N.A.
N.A.
N.A.
33.3
N.A.
P-Site Similarity:
73.3
N.A.
N.A.
N.A.
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
9
0
0
0
17
0
0
0
0
0
0
% A
% Cys:
0
17
0
0
0
0
0
0
9
0
0
0
9
0
0
% C
% Asp:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
50
0
25
0
0
0
0
0
9
9
0
0
0
9
% E
% Phe:
0
9
0
9
50
9
17
9
0
0
0
0
0
9
50
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
9
0
0
0
0
0
0
0
50
0
17
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
17
0
0
0
59
0
17
% K
% Leu:
17
0
59
0
17
0
9
9
0
0
0
17
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
50
0
17
0
0
0
0
0
0
9
0
0
% N
% Pro:
0
0
0
0
0
75
0
17
25
9
17
0
0
0
9
% P
% Gln:
0
17
0
0
0
0
0
0
9
0
0
0
0
0
0
% Q
% Arg:
9
0
0
0
0
0
67
0
17
50
0
84
0
67
0
% R
% Ser:
0
0
9
9
0
0
0
34
9
25
0
0
0
9
0
% S
% Thr:
0
0
0
0
0
0
9
34
0
0
9
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
17
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
9
% W
% Tyr:
75
0
17
9
25
0
0
0
0
9
0
0
0
9
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _