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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DGAT1
All Species:
31.52
Human Site:
S77
Identified Species:
63.03
UniProt:
O75907
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75907
NP_036211.2
488
55278
S77
R
L
Q
D
S
L
F
S
S
D
S
G
F
S
N
Chimpanzee
Pan troglodytes
XP_520014
488
54742
S77
R
L
Q
D
S
L
F
S
S
D
S
G
F
S
N
Rhesus Macaque
Macaca mulatta
XP_001090134
491
55617
S80
R
L
Q
D
S
L
F
S
S
D
S
G
F
N
N
Dog
Lupus familis
XP_849176
498
56652
S74
R
L
Q
D
S
L
F
S
S
D
S
G
F
N
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2A7
498
56772
S86
R
L
Q
D
S
L
F
S
S
D
S
G
F
S
N
Rat
Rattus norvegicus
Q9ERM3
498
56852
S86
R
L
Q
D
S
L
F
S
S
D
S
G
F
S
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_956024
499
57133
S77
K
L
Q
E
S
L
L
S
S
A
S
G
F
S
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609813
565
64925
S128
R
P
R
D
S
L
F
S
W
S
S
G
F
T
N
Honey Bee
Apis mellifera
XP_624754
498
58148
F92
R
V
D
P
W
Q
W
F
L
F
L
S
G
T
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780515
485
56246
V52
G
F
L
N
L
C
I
V
L
L
A
M
S
S
S
Poplar Tree
Populus trichocarpa
XP_002330510
493
56790
S87
V
R
E
S
P
L
S
S
D
A
I
F
K
Q
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53629
642
74004
E207
S
E
T
V
V
T
V
E
T
T
I
I
S
S
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.2
96.3
86.5
N.A.
84.7
84.7
N.A.
N.A.
N.A.
N.A.
62.5
N.A.
37.1
35.9
N.A.
35.8
Protein Similarity:
100
96.3
97.5
89.7
N.A.
90.3
90.3
N.A.
N.A.
N.A.
N.A.
74.5
N.A.
55.2
52
N.A.
53.2
P-Site Identity:
100
100
93.3
93.3
N.A.
100
100
N.A.
N.A.
N.A.
N.A.
73.3
N.A.
66.6
6.6
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
N.A.
N.A.
86.6
N.A.
80
26.6
N.A.
26.6
Percent
Protein Identity:
36.1
N.A.
N.A.
N.A.
23.2
N.A.
Protein Similarity:
54.9
N.A.
N.A.
N.A.
41.4
N.A.
P-Site Identity:
13.3
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
17
9
0
0
0
0
% A
% Cys:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
59
0
0
0
0
9
50
0
0
0
0
0
% D
% Glu:
0
9
9
9
0
0
0
9
0
0
0
0
0
0
0
% E
% Phe:
0
9
0
0
0
0
59
9
0
9
0
9
67
0
0
% F
% Gly:
9
0
0
0
0
0
0
0
0
0
0
67
9
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
9
0
0
0
17
9
0
0
0
% I
% Lys:
9
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% K
% Leu:
0
59
9
0
9
75
9
0
17
9
9
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% M
% Asn:
0
0
0
9
0
0
0
0
0
0
0
0
0
17
75
% N
% Pro:
0
9
0
9
9
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
59
0
0
9
0
0
0
0
0
0
0
9
0
% Q
% Arg:
67
9
9
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
9
0
0
9
67
0
9
75
59
9
67
9
17
59
17
% S
% Thr:
0
0
9
0
0
9
0
0
9
9
0
0
0
17
0
% T
% Val:
9
9
0
9
9
0
9
9
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
9
0
9
0
9
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _