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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DGAT1 All Species: 15.45
Human Site: Y481 Identified Species: 30.91
UniProt: O75907 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75907 NP_036211.2 488 55278 Y481 H D Y Y V L N Y E A P A A E A
Chimpanzee Pan troglodytes XP_520014 488 54742 Y481 H D Y Y V L N Y E A P A A E A
Rhesus Macaque Macaca mulatta XP_001090134 491 55617 Y484 H D Y Y V L N Y E A P V A G A
Dog Lupus familis XP_849176 498 56652 Y491 H D Y Y V L H Y E A P V V G A
Cat Felis silvestris
Mouse Mus musculus Q9Z2A7 498 56772
Rat Rattus norvegicus Q9ERM3 498 56852
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_956024 499 57133 Y490 H D Y Y V L H Y G S A S E A A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_609813 565 64925 F554 H D Y V V Q H F K N S L N G T
Honey Bee Apis mellifera XP_624754 498 58148 F487 H D Y V I T H F G E N L I E D
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780515 485 56246 A474 H D Y Y V M H A A I N V N G T
Poplar Tree Populus trichocarpa XP_002330510 493 56790 H481 M C V L L Y Y H D L M N R K G
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P53629 642 74004
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.2 96.3 86.5 N.A. 84.7 84.7 N.A. N.A. N.A. N.A. 62.5 N.A. 37.1 35.9 N.A. 35.8
Protein Similarity: 100 96.3 97.5 89.7 N.A. 90.3 90.3 N.A. N.A. N.A. N.A. 74.5 N.A. 55.2 52 N.A. 53.2
P-Site Identity: 100 100 86.6 73.3 N.A. 0 0 N.A. N.A. N.A. N.A. 53.3 N.A. 26.6 26.6 N.A. 33.3
P-Site Similarity: 100 100 86.6 80 N.A. 0 0 N.A. N.A. N.A. N.A. 73.3 N.A. 46.6 46.6 N.A. 46.6
Percent
Protein Identity: 36.1 N.A. N.A. N.A. 23.2 N.A.
Protein Similarity: 54.9 N.A. N.A. N.A. 41.4 N.A.
P-Site Identity: 0 N.A. N.A. N.A. 0 N.A.
P-Site Similarity: 26.6 N.A. N.A. N.A. 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 9 9 34 9 17 25 9 42 % A
% Cys: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 67 0 0 0 0 0 0 9 0 0 0 0 0 9 % D
% Glu: 0 0 0 0 0 0 0 0 34 9 0 0 9 25 0 % E
% Phe: 0 0 0 0 0 0 0 17 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 17 0 0 0 0 34 9 % G
% His: 67 0 0 0 0 0 42 9 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 9 0 0 0 0 9 0 0 9 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 9 0 0 0 0 9 0 % K
% Leu: 0 0 0 9 9 42 0 0 0 9 0 17 0 0 0 % L
% Met: 9 0 0 0 0 9 0 0 0 0 9 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 25 0 0 9 17 9 17 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 34 0 0 0 0 % P
% Gln: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 9 9 9 0 0 0 % S
% Thr: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 17 % T
% Val: 0 0 9 17 59 0 0 0 0 0 0 25 9 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 67 50 0 9 9 42 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _