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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CCNK
All Species:
29.39
Human Site:
S259
Identified Species:
49.74
UniProt:
O75909
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75909
NP_001092872.1
580
64240
S259
H
Q
I
L
D
L
Y
S
Q
G
K
Q
Q
M
P
Chimpanzee
Pan troglodytes
Q8HXN7
725
80550
T237
L
E
L
L
D
E
L
T
H
E
F
L
Q
I
L
Rhesus Macaque
Macaca mulatta
XP_001107367
364
39075
V122
R
Q
V
K
R
A
V
V
V
S
P
K
E
E
N
Dog
Lupus familis
XP_855304
524
57823
S259
H
Q
I
L
D
L
Y
S
Q
G
K
Q
Q
M
P
Cat
Felis silvestris
Mouse
Mus musculus
O88874
554
61358
S259
H
Q
I
L
D
L
Y
S
Q
G
K
Q
Q
M
P
Rat
Rattus norvegicus
NP_001103142
589
65348
S259
H
Q
I
L
D
L
Y
S
Q
G
K
Q
Q
M
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515372
370
42548
Q128
R
S
L
L
N
D
V
Q
F
G
Q
F
G
D
D
Chicken
Gallus gallus
NP_001026380
587
65568
S259
H
Q
I
L
D
L
Y
S
Q
G
K
Q
Q
M
P
Frog
Xenopus laevis
NP_001089373
573
63498
S259
H
Q
I
L
D
L
Y
S
Q
G
K
Q
Q
M
P
Zebra Danio
Brachydanio rerio
NP_001157251
539
59655
S260
H
Q
I
L
D
L
Y
S
Q
G
K
Q
P
I
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_788082
400
44760
L158
F
K
G
D
Q
Q
K
L
Q
K
M
V
Q
M
A
Honey Bee
Apis mellifera
XP_394536
414
46785
S172
A
W
T
F
V
N
D
S
L
C
T
T
L
S
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001195649
785
86423
A239
H
K
L
L
D
L
Y
A
A
G
Q
H
K
G
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FKE6
579
65168
A274
Y
E
Q
N
R
V
P
A
S
Q
G
S
E
V
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
21.1
62.7
66.2
N.A.
91.3
94.4
N.A.
60.3
89.9
82.7
70.3
N.A.
41
42.5
N.A.
38.7
Protein Similarity:
100
36.1
62.7
69.8
N.A.
92
95.2
N.A.
60.6
92.5
88.7
77.2
N.A.
52
52.9
N.A.
48
P-Site Identity:
100
20
6.6
100
N.A.
100
100
N.A.
13.3
100
100
86.6
N.A.
20
6.6
N.A.
46.6
P-Site Similarity:
100
46.6
26.6
100
N.A.
100
100
N.A.
33.3
100
100
93.3
N.A.
26.6
6.6
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
21
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
8
0
15
8
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
0
0
0
8
65
8
8
0
0
0
0
0
0
8
8
% D
% Glu:
0
15
0
0
0
8
0
0
0
8
0
0
15
8
8
% E
% Phe:
8
0
0
8
0
0
0
0
8
0
8
8
0
0
0
% F
% Gly:
0
0
8
0
0
0
0
0
0
65
8
0
8
8
0
% G
% His:
58
0
0
0
0
0
0
0
8
0
0
8
0
0
0
% H
% Ile:
0
0
50
0
0
0
0
0
0
0
0
0
0
15
0
% I
% Lys:
0
15
0
8
0
0
8
0
0
8
50
8
8
0
0
% K
% Leu:
8
0
22
72
0
58
8
8
8
0
0
8
8
0
15
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
0
50
0
% M
% Asn:
0
0
0
8
8
8
0
0
0
0
0
0
0
0
8
% N
% Pro:
0
0
0
0
0
0
8
0
0
0
8
0
8
0
58
% P
% Gln:
0
58
8
0
8
8
0
8
58
8
15
50
58
0
0
% Q
% Arg:
15
0
0
0
15
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
8
0
0
0
0
0
58
8
8
0
8
0
8
0
% S
% Thr:
0
0
8
0
0
0
0
8
0
0
8
8
0
0
0
% T
% Val:
0
0
8
0
8
8
15
8
8
0
0
8
0
8
0
% V
% Trp:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
58
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _