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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CCNK All Species: 25.45
Human Site: S427 Identified Species: 43.08
UniProt: O75909 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75909 NP_001092872.1 580 64240 S427 P P P P P P S S Y M T G M S T
Chimpanzee Pan troglodytes Q8HXN7 725 80550 T594 P A K I A K S T K S S S L N F
Rhesus Macaque Macaca mulatta XP_001107367 364 39075 S241 M M K T E G P S Y G A L P P A
Dog Lupus familis XP_855304 524 57823 P396 P P P A I P P P T P G Y P P P
Cat Felis silvestris
Mouse Mus musculus O88874 554 61358 S429 P P P P P P S S Y M T G M S T
Rat Rattus norvegicus NP_001103142 589 65348 S436 P P P P P P S S Y M T G M S T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515372 370 42548 L247 Q D V P V D V L E D I C H Q I
Chicken Gallus gallus NP_001026380 587 65568 S436 P P P P P P T S Y I T G M S T
Frog Xenopus laevis NP_001089373 573 63498 S421 P P P P P P A S Y I T G M S T
Zebra Danio Brachydanio rerio NP_001157251 539 59655 S403 P P P P P P S S Y I M G M S T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_788082 400 44760 L277 N S T G I G P L S V P Q Q P P
Honey Bee Apis mellifera XP_394536 414 46785 A291 V T K V E A A A V S S N G C L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001195649 785 86423 A487 Y A A P Q Y S A P H Y S T G S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FKE6 579 65168 T449 K K L L G E R T R K K D L M D
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 21.1 62.7 66.2 N.A. 91.3 94.4 N.A. 60.3 89.9 82.7 70.3 N.A. 41 42.5 N.A. 38.7
Protein Similarity: 100 36.1 62.7 69.8 N.A. 92 95.2 N.A. 60.6 92.5 88.7 77.2 N.A. 52 52.9 N.A. 48
P-Site Identity: 100 13.3 13.3 26.6 N.A. 100 100 N.A. 6.6 86.6 86.6 86.6 N.A. 0 0 N.A. 13.3
P-Site Similarity: 100 40 13.3 26.6 N.A. 100 100 N.A. 6.6 100 100 93.3 N.A. 6.6 20 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. 21 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 36.5 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 15 8 8 8 8 15 15 0 0 8 0 0 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 8 0 8 0 % C
% Asp: 0 8 0 0 0 8 0 0 0 8 0 8 0 0 8 % D
% Glu: 0 0 0 0 15 8 0 0 8 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % F
% Gly: 0 0 0 8 8 15 0 0 0 8 8 43 8 8 0 % G
% His: 0 0 0 0 0 0 0 0 0 8 0 0 8 0 0 % H
% Ile: 0 0 0 8 15 0 0 0 0 22 8 0 0 0 8 % I
% Lys: 8 8 22 0 0 8 0 0 8 8 8 0 0 0 0 % K
% Leu: 0 0 8 8 0 0 0 15 0 0 0 8 15 0 8 % L
% Met: 8 8 0 0 0 0 0 0 0 22 8 0 43 8 0 % M
% Asn: 8 0 0 0 0 0 0 0 0 0 0 8 0 8 0 % N
% Pro: 58 50 50 58 43 50 22 8 8 8 8 0 15 22 15 % P
% Gln: 8 0 0 0 8 0 0 0 0 0 0 8 8 8 0 % Q
% Arg: 0 0 0 0 0 0 8 0 8 0 0 0 0 0 0 % R
% Ser: 0 8 0 0 0 0 43 50 8 15 15 15 0 43 8 % S
% Thr: 0 8 8 8 0 0 8 15 8 0 36 0 8 0 43 % T
% Val: 8 0 8 8 8 0 8 0 8 8 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 0 0 8 0 0 50 0 8 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _