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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CCNK All Species: 24.24
Human Site: T453 Identified Species: 41.03
UniProt: O75909 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75909 NP_001092872.1 580 64240 T453 S L Q S M M K T E G P S Y G A
Chimpanzee Pan troglodytes Q8HXN7 725 80550 S620 P G H S S D T S G L S F S Q P
Rhesus Macaque Macaca mulatta XP_001107367 364 39075 P267 H V Y P P N P P P P P V P P P
Dog Lupus familis XP_855304 524 57823 H422 P P R L P P T H A V P P H P P
Cat Felis silvestris
Mouse Mus musculus O88874 554 61358 T455 S L Q S M M K T E G P S Y G A
Rat Rattus norvegicus NP_001103142 589 65348 T462 S L Q S M M K T E G P S Y G A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515372 370 42548 L273 P H H T P H Q L Q Q P P S L Q
Chicken Gallus gallus NP_001026380 587 65568 T462 S L Q S M M K T E G P T Y G A
Frog Xenopus laevis NP_001089373 573 63498 T447 S L Q S M M K T E G P S Y G S
Zebra Danio Brachydanio rerio NP_001157251 539 59655 T429 S L Q S M M K T E G P S Y A P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_788082 400 44760 K303 V S N I Q S I K S L A S G V P
Honey Bee Apis mellifera XP_394536 414 46785 T317 D V P T H F P T Y P A N Y A P
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001195649 785 86423 P513 T Q P V I P P P A P A P A P V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FKE6 579 65168 E475 V Q L A V E D E K T K E R K V
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 21.1 62.7 66.2 N.A. 91.3 94.4 N.A. 60.3 89.9 82.7 70.3 N.A. 41 42.5 N.A. 38.7
Protein Similarity: 100 36.1 62.7 69.8 N.A. 92 95.2 N.A. 60.6 92.5 88.7 77.2 N.A. 52 52.9 N.A. 48
P-Site Identity: 100 6.6 6.6 6.6 N.A. 100 100 N.A. 6.6 93.3 93.3 86.6 N.A. 6.6 13.3 N.A. 0
P-Site Similarity: 100 13.3 13.3 20 N.A. 100 100 N.A. 26.6 100 100 86.6 N.A. 6.6 33.3 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. 21 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 36.5 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 0 0 0 0 15 0 22 0 8 15 29 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 0 0 0 8 8 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 8 0 8 43 0 0 8 0 0 0 % E
% Phe: 0 0 0 0 0 8 0 0 0 0 0 8 0 0 0 % F
% Gly: 0 8 0 0 0 0 0 0 8 43 0 0 8 36 0 % G
% His: 8 8 15 0 8 8 0 8 0 0 0 0 8 0 0 % H
% Ile: 0 0 0 8 8 0 8 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 43 8 8 0 8 0 0 8 0 % K
% Leu: 0 43 8 8 0 0 0 8 0 15 0 0 0 8 0 % L
% Met: 0 0 0 0 43 43 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 8 0 0 8 0 0 0 0 0 8 0 0 0 % N
% Pro: 22 8 15 8 22 15 22 15 8 22 65 22 8 22 43 % P
% Gln: 0 15 43 0 8 0 8 0 8 8 0 0 0 8 8 % Q
% Arg: 0 0 8 0 0 0 0 0 0 0 0 0 8 0 0 % R
% Ser: 43 8 0 50 8 8 0 8 8 0 8 43 15 0 8 % S
% Thr: 8 0 0 15 0 0 15 50 0 8 0 8 0 0 0 % T
% Val: 15 15 0 8 8 0 0 0 0 8 0 8 0 8 15 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 8 0 0 0 0 0 8 0 0 0 50 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _