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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHRS3
All Species:
36.67
Human Site:
S143
Identified Species:
80.67
UniProt:
O75911
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75911
NP_004744.2
302
33548
S143
D
D
D
A
L
L
K
S
Q
H
I
N
T
L
G
Chimpanzee
Pan troglodytes
XP_001145518
303
33686
S144
D
D
D
A
L
L
K
S
Q
H
I
N
T
L
G
Rhesus Macaque
Macaca mulatta
XP_001105958
302
33498
S143
D
D
D
A
L
L
K
S
Q
H
I
N
T
L
G
Dog
Lupus familis
XP_544561
302
33482
S143
D
D
D
A
L
L
K
S
Q
H
I
N
T
L
G
Cat
Felis silvestris
Mouse
Mus musculus
O88876
302
33634
S143
D
D
D
A
L
L
K
S
Q
H
V
N
T
L
G
Rat
Rattus norvegicus
Q80ZF7
341
38043
T165
P
D
E
L
I
E
R
T
M
M
V
N
C
H
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511714
304
33773
S145
D
D
D
A
L
L
K
S
Q
H
I
N
T
L
G
Chicken
Gallus gallus
XP_417636
302
33553
S143
D
D
D
A
L
L
K
S
Q
H
I
N
T
L
G
Frog
Xenopus laevis
Q6DCT3
341
38425
T165
P
D
E
L
I
E
R
T
M
M
V
N
C
H
A
Zebra Danio
Brachydanio rerio
Q7T2D1
336
37801
T160
P
D
E
L
I
E
R
T
M
M
V
N
C
H
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_794417
334
37108
T158
N
E
E
D
F
H
K
T
L
N
V
N
S
L
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
99.6
98
N.A.
95
33.4
N.A.
93
90
34.5
36.3
N.A.
N.A.
N.A.
N.A.
35.9
Protein Similarity:
100
99.6
100
99
N.A.
97.6
51.9
N.A.
96.3
96
52.2
52.3
N.A.
N.A.
N.A.
N.A.
54.7
P-Site Identity:
100
100
100
100
N.A.
93.3
13.3
N.A.
100
100
13.3
13.3
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
100
100
100
N.A.
100
46.6
N.A.
100
100
46.6
46.6
N.A.
N.A.
N.A.
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
64
0
0
0
0
0
0
0
0
0
0
37
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
28
0
0
% C
% Asp:
64
91
64
10
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
10
37
0
0
28
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
64
% G
% His:
0
0
0
0
0
10
0
0
0
64
0
0
0
28
0
% H
% Ile:
0
0
0
0
28
0
0
0
0
0
55
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
73
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
28
64
64
0
0
10
0
0
0
0
73
0
% L
% Met:
0
0
0
0
0
0
0
0
28
28
0
0
0
0
0
% M
% Asn:
10
0
0
0
0
0
0
0
0
10
0
100
0
0
0
% N
% Pro:
28
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
64
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
28
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
64
0
0
0
0
10
0
0
% S
% Thr:
0
0
0
0
0
0
0
37
0
0
0
0
64
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
46
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _