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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DGKI
All Species:
19.09
Human Site:
S204
Identified Species:
35
UniProt:
O75912
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75912
NP_004708.1
1065
116997
S204
C
Q
V
R
F
A
K
S
A
L
R
R
K
C
A
Chimpanzee
Pan troglodytes
XP_001147695
1066
117064
S205
C
Q
V
R
F
A
K
S
A
L
R
R
K
C
A
Rhesus Macaque
Macaca mulatta
XP_001107030
1066
117055
S205
C
Q
V
R
F
A
K
S
A
L
R
R
K
C
A
Dog
Lupus familis
XP_539825
1017
113427
S164
C
Q
V
R
F
A
K
S
A
L
R
R
K
C
A
Cat
Felis silvestris
Mouse
Mus musculus
Q80UP3
929
104029
P155
K
I
N
F
R
C
K
P
S
F
R
E
S
G
S
Rat
Rattus norvegicus
O08560
929
103991
P155
K
I
N
F
R
C
K
P
S
F
R
E
S
G
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513139
955
107141
I162
H
S
K
E
I
V
A
I
S
C
S
W
C
K
Q
Chicken
Gallus gallus
XP_416357
1074
118933
S198
C
Q
V
K
F
S
K
S
A
L
R
R
K
C
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001922445
1086
121319
K167
C
Y
A
K
S
L
Q
K
S
V
A
R
K
K
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q09103
1457
160124
N530
F
L
T
V
P
N
I
N
A
T
R
S
R
S
V
Honey Bee
Apis mellifera
XP_396522
837
92900
G63
K
G
K
C
A
N
C
G
K
S
F
Q
S
K
L
Nematode Worm
Caenorhab. elegans
Q10024
937
105180
T162
S
I
S
N
P
D
L
T
N
C
Q
I
K
Q
M
Sea Urchin
Strong. purpuratus
XP_796061
815
92455
R41
S
H
A
L
K
A
T
R
H
G
M
F
T
K
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.4
86.4
N.A.
55.5
56.6
N.A.
75.4
80.7
N.A.
56.6
N.A.
31.6
34.1
34
43.3
Protein Similarity:
100
99.9
99.6
89.1
N.A.
69.3
69.3
N.A.
80.9
86.4
N.A.
69.1
N.A.
44.5
49.4
49.6
55.9
P-Site Identity:
100
100
100
100
N.A.
13.3
13.3
N.A.
0
86.6
N.A.
20
N.A.
13.3
0
6.6
6.6
P-Site Similarity:
100
100
100
100
N.A.
26.6
26.6
N.A.
6.6
100
N.A.
46.6
N.A.
26.6
6.6
20
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
16
0
8
39
8
0
47
0
8
0
0
0
39
% A
% Cys:
47
0
0
8
0
16
8
0
0
16
0
0
8
39
8
% C
% Asp:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
8
0
0
0
0
0
0
0
16
0
0
0
% E
% Phe:
8
0
0
16
39
0
0
0
0
16
8
8
0
0
0
% F
% Gly:
0
8
0
0
0
0
0
8
0
8
0
0
0
16
0
% G
% His:
8
8
0
0
0
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
0
24
0
0
8
0
8
8
0
0
0
8
0
0
0
% I
% Lys:
24
0
16
16
8
0
54
8
8
0
0
0
54
31
0
% K
% Leu:
0
8
0
8
0
8
8
0
0
39
0
0
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
8
% M
% Asn:
0
0
16
8
0
16
0
8
8
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
16
0
0
16
0
0
0
0
0
0
0
% P
% Gln:
0
39
0
0
0
0
8
0
0
0
8
8
0
8
8
% Q
% Arg:
0
0
0
31
16
0
0
8
0
0
62
47
8
0
0
% R
% Ser:
16
8
8
0
8
8
0
39
31
8
8
8
24
8
16
% S
% Thr:
0
0
8
0
0
0
8
8
0
8
0
0
8
0
0
% T
% Val:
0
0
39
8
0
8
0
0
0
8
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _