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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DGKI
All Species:
17.88
Human Site:
S351
Identified Species:
32.78
UniProt:
O75912
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75912
NP_004708.1
1065
116997
S351
T
S
F
K
R
K
A
S
K
R
G
M
E
Q
E
Chimpanzee
Pan troglodytes
XP_001147695
1066
117064
S352
T
S
F
K
R
K
A
S
K
R
G
M
E
Q
E
Rhesus Macaque
Macaca mulatta
XP_001107030
1066
117055
S352
T
S
F
K
R
K
A
S
K
R
G
M
E
Q
E
Dog
Lupus familis
XP_539825
1017
113427
S311
T
S
F
K
R
K
A
S
K
R
G
T
E
Q
E
Cat
Felis silvestris
Mouse
Mus musculus
Q80UP3
929
104029
F284
E
E
G
R
W
R
P
F
I
I
R
P
T
P
S
Rat
Rattus norvegicus
O08560
929
103991
F284
E
E
G
R
W
R
P
F
I
I
R
P
T
P
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513139
955
107141
K292
D
L
S
Q
E
G
P
K
D
A
L
E
L
Y
R
Chicken
Gallus gallus
XP_416357
1074
118933
S345
T
S
F
K
R
K
A
S
K
R
G
N
D
L
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001922445
1086
121319
K340
S
F
K
R
K
S
S
K
K
G
A
E
E
A
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q09103
1457
160124
G766
N
A
A
S
G
S
G
G
G
G
A
G
G
G
A
Honey Bee
Apis mellifera
XP_396522
837
92900
S192
L
V
F
I
N
P
K
S
G
G
N
Q
G
A
K
Nematode Worm
Caenorhab. elegans
Q10024
937
105180
P291
D
Y
A
T
K
K
T
P
S
K
E
S
T
D
G
Sea Urchin
Strong. purpuratus
XP_796061
815
92455
P170
R
I
N
F
K
C
K
P
T
F
R
D
A
G
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.4
86.4
N.A.
55.5
56.6
N.A.
75.4
80.7
N.A.
56.6
N.A.
31.6
34.1
34
43.3
Protein Similarity:
100
99.9
99.6
89.1
N.A.
69.3
69.3
N.A.
80.9
86.4
N.A.
69.1
N.A.
44.5
49.4
49.6
55.9
P-Site Identity:
100
100
100
93.3
N.A.
0
0
N.A.
0
73.3
N.A.
13.3
N.A.
0
13.3
6.6
0
P-Site Similarity:
100
100
100
93.3
N.A.
13.3
13.3
N.A.
6.6
80
N.A.
40
N.A.
6.6
20
20
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
16
0
0
0
39
0
0
8
16
0
8
16
8
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
16
0
0
0
0
0
0
0
8
0
0
8
8
8
0
% D
% Glu:
16
16
0
0
8
0
0
0
0
0
8
16
39
0
31
% E
% Phe:
0
8
47
8
0
0
0
16
0
8
0
0
0
0
8
% F
% Gly:
0
0
16
0
8
8
8
8
16
24
39
8
16
16
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
8
0
0
0
0
16
16
0
0
0
0
8
% I
% Lys:
0
0
8
39
24
47
16
16
47
8
0
0
0
0
8
% K
% Leu:
8
8
0
0
0
0
0
0
0
0
8
0
8
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
24
0
0
0
% M
% Asn:
8
0
8
0
8
0
0
0
0
0
8
8
0
0
0
% N
% Pro:
0
0
0
0
0
8
24
16
0
0
0
16
0
16
0
% P
% Gln:
0
0
0
8
0
0
0
0
0
0
0
8
0
31
0
% Q
% Arg:
8
0
0
24
39
16
0
0
0
39
24
0
0
0
16
% R
% Ser:
8
39
8
8
0
16
8
47
8
0
0
8
0
0
16
% S
% Thr:
39
0
0
8
0
0
8
0
8
0
0
8
24
0
0
% T
% Val:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
16
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _