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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DGKI All Species: 11.82
Human Site: S57 Identified Species: 21.67
UniProt: O75912 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75912 NP_004708.1 1065 116997 S57 A G A M N P S S S A G E E K G
Chimpanzee Pan troglodytes XP_001147695 1066 117064 S58 A G A M N P S S S A G E E K G
Rhesus Macaque Macaca mulatta XP_001107030 1066 117055 S58 V G A M N P S S S A G E E K G
Dog Lupus familis XP_539825 1017 113427 S34 E E L F A M E S G S G C P G A
Cat Felis silvestris
Mouse Mus musculus Q80UP3 929 104029 E26 S A S S S G S E R D A G P E P
Rat Rattus norvegicus O08560 929 103991 E26 S A S S S G S E R D A D P E P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513139 955 107141 V33 G P S L S L P V S N G P V K E
Chicken Gallus gallus XP_416357 1074 118933 T37 P G S G R P P T P D G P Q R L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001922445 1086 121319 V36 P P A L E D V V E E E D V F L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q09103 1457 160124 L130 A G F L Q V P L A A H Q Q R S
Honey Bee Apis mellifera XP_396522 837 92900
Nematode Worm Caenorhab. elegans Q10024 937 105180 F33 A A E R R S Q F A R V P A R S
Sea Urchin Strong. purpuratus XP_796061 815 92455
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 99.4 86.4 N.A. 55.5 56.6 N.A. 75.4 80.7 N.A. 56.6 N.A. 31.6 34.1 34 43.3
Protein Similarity: 100 99.9 99.6 89.1 N.A. 69.3 69.3 N.A. 80.9 86.4 N.A. 69.1 N.A. 44.5 49.4 49.6 55.9
P-Site Identity: 100 100 93.3 13.3 N.A. 6.6 6.6 N.A. 20 20 N.A. 6.6 N.A. 20 0 6.6 0
P-Site Similarity: 100 100 93.3 20 N.A. 33.3 40 N.A. 40 46.6 N.A. 20 N.A. 53.3 0 20 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 31 24 31 0 8 0 0 0 16 31 16 0 8 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % C
% Asp: 0 0 0 0 0 8 0 0 0 24 0 16 0 0 0 % D
% Glu: 8 8 8 0 8 0 8 16 8 8 8 24 24 16 8 % E
% Phe: 0 0 8 8 0 0 0 8 0 0 0 0 0 8 0 % F
% Gly: 8 39 0 8 0 16 0 0 8 0 47 8 0 8 24 % G
% His: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 31 0 % K
% Leu: 0 0 8 24 0 8 0 8 0 0 0 0 0 0 16 % L
% Met: 0 0 0 24 0 8 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 24 0 0 0 0 8 0 0 0 0 0 % N
% Pro: 16 16 0 0 0 31 24 0 8 0 0 24 24 0 16 % P
% Gln: 0 0 0 0 8 0 8 0 0 0 0 8 16 0 0 % Q
% Arg: 0 0 0 8 16 0 0 0 16 8 0 0 0 24 0 % R
% Ser: 16 0 31 16 24 8 39 31 31 8 0 0 0 0 16 % S
% Thr: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % T
% Val: 8 0 0 0 0 8 8 16 0 0 8 0 16 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _