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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DGKI
All Species:
24.24
Human Site:
S577
Identified Species:
44.44
UniProt:
O75912
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75912
NP_004708.1
1065
116997
S577
S
D
F
L
Q
R
S
S
R
D
L
S
K
H
V
Chimpanzee
Pan troglodytes
XP_001147695
1066
117064
S578
S
D
F
L
Q
R
S
S
R
D
L
S
K
H
V
Rhesus Macaque
Macaca mulatta
XP_001107030
1066
117055
S578
S
D
F
L
Q
R
S
S
R
D
L
S
K
H
V
Dog
Lupus familis
XP_539825
1017
113427
S537
S
D
F
L
Q
R
S
S
R
D
L
S
K
H
V
Cat
Felis silvestris
Mouse
Mus musculus
Q80UP3
929
104029
M483
N
S
R
F
R
N
K
M
F
Y
A
G
T
A
F
Rat
Rattus norvegicus
O08560
929
103991
M483
N
S
R
F
R
N
K
M
F
Y
A
G
T
A
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513139
955
107141
A492
L
N
I
P
R
Y
C
A
G
T
M
P
W
G
N
Chicken
Gallus gallus
XP_416357
1074
118933
S578
S
D
F
L
Q
R
S
S
R
D
L
S
K
H
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001922445
1086
121319
S565
S
D
F
L
M
G
S
S
K
D
L
A
K
H
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q09103
1457
160124
S994
A
H
P
E
R
F
N
S
R
L
R
N
K
M
Y
Honey Bee
Apis mellifera
XP_396522
837
92900
F391
K
W
K
D
L
S
E
F
V
M
L
D
C
D
G
Nematode Worm
Caenorhab. elegans
Q10024
937
105180
D490
G
W
V
L
S
T
L
D
N
L
N
W
P
A
Y
Sea Urchin
Strong. purpuratus
XP_796061
815
92455
C369
P
N
L
R
I
L
A
C
G
G
D
G
T
V
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.4
86.4
N.A.
55.5
56.6
N.A.
75.4
80.7
N.A.
56.6
N.A.
31.6
34.1
34
43.3
Protein Similarity:
100
99.9
99.6
89.1
N.A.
69.3
69.3
N.A.
80.9
86.4
N.A.
69.1
N.A.
44.5
49.4
49.6
55.9
P-Site Identity:
100
100
100
100
N.A.
0
0
N.A.
0
100
N.A.
66.6
N.A.
20
6.6
6.6
0
P-Site Similarity:
100
100
100
100
N.A.
13.3
13.3
N.A.
26.6
100
N.A.
86.6
N.A.
46.6
6.6
6.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
8
8
0
0
16
8
0
24
0
% A
% Cys:
0
0
0
0
0
0
8
8
0
0
0
0
8
0
0
% C
% Asp:
0
47
0
8
0
0
0
8
0
47
8
8
0
8
0
% D
% Glu:
0
0
0
8
0
0
8
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
47
16
0
8
0
8
16
0
0
0
0
0
16
% F
% Gly:
8
0
0
0
0
8
0
0
16
8
0
24
0
8
16
% G
% His:
0
8
0
0
0
0
0
0
0
0
0
0
0
47
0
% H
% Ile:
0
0
8
0
8
0
0
0
0
0
0
0
0
0
8
% I
% Lys:
8
0
8
0
0
0
16
0
8
0
0
0
54
0
0
% K
% Leu:
8
0
8
54
8
8
8
0
0
16
54
0
0
0
0
% L
% Met:
0
0
0
0
8
0
0
16
0
8
8
0
0
8
0
% M
% Asn:
16
16
0
0
0
16
8
0
8
0
8
8
0
0
8
% N
% Pro:
8
0
8
8
0
0
0
0
0
0
0
8
8
0
0
% P
% Gln:
0
0
0
0
39
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
16
8
31
39
0
0
47
0
8
0
0
0
0
% R
% Ser:
47
16
0
0
8
8
47
54
0
0
0
39
0
0
0
% S
% Thr:
0
0
0
0
0
8
0
0
0
8
0
0
24
0
0
% T
% Val:
0
0
8
0
0
0
0
0
8
0
0
0
0
8
39
% V
% Trp:
0
16
0
0
0
0
0
0
0
0
0
8
8
0
0
% W
% Tyr:
0
0
0
0
0
8
0
0
0
16
0
0
0
0
16
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _