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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DGKI
All Species:
16.97
Human Site:
S750
Identified Species:
31.11
UniProt:
O75912
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75912
NP_004708.1
1065
116997
S750
K
E
K
L
R
E
A
S
I
S
D
W
L
R
T
Chimpanzee
Pan troglodytes
XP_001147695
1066
117064
S751
K
E
K
L
R
E
A
S
I
S
D
W
L
R
T
Rhesus Macaque
Macaca mulatta
XP_001107030
1066
117055
S751
K
E
K
L
R
E
A
S
I
S
D
W
L
R
T
Dog
Lupus familis
XP_539825
1017
113427
K705
G
F
H
Y
D
K
E
K
L
R
E
A
S
I
P
Cat
Felis silvestris
Mouse
Mus musculus
Q80UP3
929
104029
P633
A
K
R
R
S
T
A
P
L
H
S
D
Q
Q
P
Rat
Rattus norvegicus
O08560
929
103991
P633
A
K
R
R
S
T
A
P
L
H
S
D
Q
Q
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513139
955
107141
K643
G
L
H
Y
D
K
E
K
L
R
E
A
S
L
P
Chicken
Gallus gallus
XP_416357
1074
118933
Y751
K
E
K
L
R
E
A
Y
I
S
E
Y
L
K
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001922445
1086
121319
S738
K
E
K
L
K
E
A
S
I
P
L
G
L
I
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q09103
1457
160124
V1147
R
K
H
G
R
G
D
V
Q
V
N
P
L
E
K
Honey Bee
Apis mellifera
XP_396522
837
92900
H541
M
S
D
Y
E
R
Y
H
H
D
K
D
M
L
K
Nematode Worm
Caenorhab. elegans
Q10024
937
105180
T640
E
C
D
G
V
D
V
T
P
R
I
K
E
L
K
Sea Urchin
Strong. purpuratus
XP_796061
815
92455
K519
R
A
S
K
D
L
T
K
K
I
T
L
E
C
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.4
86.4
N.A.
55.5
56.6
N.A.
75.4
80.7
N.A.
56.6
N.A.
31.6
34.1
34
43.3
Protein Similarity:
100
99.9
99.6
89.1
N.A.
69.3
69.3
N.A.
80.9
86.4
N.A.
69.1
N.A.
44.5
49.4
49.6
55.9
P-Site Identity:
100
100
100
0
N.A.
6.6
6.6
N.A.
0
66.6
N.A.
60
N.A.
13.3
0
0
0
P-Site Similarity:
100
100
100
20
N.A.
33.3
33.3
N.A.
20
86.6
N.A.
66.6
N.A.
33.3
6.6
20
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
8
0
0
0
0
54
0
0
0
0
16
0
0
0
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
0
0
16
0
24
8
8
0
0
8
24
24
0
0
8
% D
% Glu:
8
39
0
0
8
39
16
0
0
0
24
0
16
8
8
% E
% Phe:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
16
0
0
16
0
8
0
0
0
0
0
8
0
0
0
% G
% His:
0
0
24
0
0
0
0
8
8
16
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
39
8
8
0
0
16
0
% I
% Lys:
39
24
39
8
8
16
0
24
8
0
8
8
0
8
24
% K
% Leu:
0
8
0
39
0
8
0
0
31
0
8
8
47
24
0
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
16
8
8
0
8
0
0
31
% P
% Gln:
0
0
0
0
0
0
0
0
8
0
0
0
16
16
0
% Q
% Arg:
16
0
16
16
39
8
0
0
0
24
0
0
0
24
0
% R
% Ser:
0
8
8
0
16
0
0
31
0
31
16
0
16
0
0
% S
% Thr:
0
0
0
0
0
16
8
8
0
0
8
0
0
0
24
% T
% Val:
0
0
0
0
8
0
8
8
0
8
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
24
0
0
0
% W
% Tyr:
0
0
0
24
0
0
8
8
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _