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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DGKI
All Species:
15.15
Human Site:
S825
Identified Species:
27.78
UniProt:
O75912
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75912
NP_004708.1
1065
116997
S825
A
L
S
A
Q
R
L
S
P
R
W
C
F
L
D
Chimpanzee
Pan troglodytes
XP_001147695
1066
117064
S826
A
L
S
A
Q
R
L
S
P
R
W
C
F
L
D
Rhesus Macaque
Macaca mulatta
XP_001107030
1066
117055
S826
A
L
S
A
Q
R
L
S
P
R
W
C
F
L
D
Dog
Lupus familis
XP_539825
1017
113427
S777
W
C
F
L
D
A
T
S
A
D
R
F
Y
R
I
Cat
Felis silvestris
Mouse
Mus musculus
Q80UP3
929
104029
A704
R
E
P
D
G
A
G
A
K
S
P
M
C
H
Q
Rat
Rattus norvegicus
O08560
929
103991
A704
Q
E
P
D
G
A
G
A
K
S
P
M
C
H
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513139
955
107141
S715
W
C
F
L
D
A
T
S
A
D
R
F
Y
R
I
Chicken
Gallus gallus
XP_416357
1074
118933
S833
V
L
S
V
Q
R
L
S
P
R
W
C
F
L
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001922445
1086
121319
T830
V
V
T
E
T
V
S
T
S
P
G
M
P
D
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q09103
1457
160124
C1220
P
K
V
S
Q
D
W
C
F
I
D
S
C
T
A
Honey Bee
Apis mellifera
XP_396522
837
92900
V612
H
Y
V
T
D
V
A
V
E
T
V
Y
V
L
E
Nematode Worm
Caenorhab. elegans
Q10024
937
105180
I712
Q
C
S
R
V
R
V
I
T
N
K
A
I
P
M
Sea Urchin
Strong. purpuratus
XP_796061
815
92455
V590
S
Q
I
A
A
L
Y
V
G
G
H
G
E
R
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.4
86.4
N.A.
55.5
56.6
N.A.
75.4
80.7
N.A.
56.6
N.A.
31.6
34.1
34
43.3
Protein Similarity:
100
99.9
99.6
89.1
N.A.
69.3
69.3
N.A.
80.9
86.4
N.A.
69.1
N.A.
44.5
49.4
49.6
55.9
P-Site Identity:
100
100
100
6.6
N.A.
0
0
N.A.
6.6
86.6
N.A.
0
N.A.
6.6
6.6
13.3
6.6
P-Site Similarity:
100
100
100
13.3
N.A.
6.6
6.6
N.A.
13.3
86.6
N.A.
20
N.A.
13.3
13.3
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
24
0
0
31
8
31
8
16
16
0
0
8
0
0
8
% A
% Cys:
0
24
0
0
0
0
0
8
0
0
0
31
24
0
0
% C
% Asp:
0
0
0
16
24
8
0
0
0
16
8
0
0
8
31
% D
% Glu:
0
16
0
8
0
0
0
0
8
0
0
0
8
0
8
% E
% Phe:
0
0
16
0
0
0
0
0
8
0
0
16
31
0
0
% F
% Gly:
0
0
0
0
16
0
16
0
8
8
8
8
0
0
0
% G
% His:
8
0
0
0
0
0
0
0
0
0
8
0
0
16
0
% H
% Ile:
0
0
8
0
0
0
0
8
0
8
0
0
8
0
24
% I
% Lys:
0
8
0
0
0
0
0
0
16
0
8
0
0
0
0
% K
% Leu:
0
31
0
16
0
8
31
0
0
0
0
0
0
39
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
24
0
0
8
% M
% Asn:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% N
% Pro:
8
0
16
0
0
0
0
0
31
8
16
0
8
8
8
% P
% Gln:
16
8
0
0
39
0
0
0
0
0
0
0
0
0
8
% Q
% Arg:
8
0
0
8
0
39
0
0
0
31
16
0
0
24
0
% R
% Ser:
8
0
39
8
0
0
8
47
8
16
0
8
0
0
0
% S
% Thr:
0
0
8
8
8
0
16
8
8
8
0
0
0
8
0
% T
% Val:
16
8
16
8
8
16
8
16
0
0
8
0
8
0
0
% V
% Trp:
16
0
0
0
0
0
8
0
0
0
31
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
8
0
0
0
0
8
16
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _