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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DGKI
All Species:
19.09
Human Site:
S860
Identified Species:
35
UniProt:
O75912
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75912
NP_004708.1
1065
116997
S860
L
D
P
D
M
V
V
S
Q
P
A
G
T
P
P
Chimpanzee
Pan troglodytes
XP_001147695
1066
117064
S861
L
D
P
D
M
V
V
S
Q
P
A
G
T
P
P
Rhesus Macaque
Macaca mulatta
XP_001107030
1066
117055
S861
L
D
P
D
M
V
V
S
Q
P
A
G
T
P
P
Dog
Lupus familis
XP_539825
1017
113427
S812
L
D
P
D
M
V
L
S
Q
Q
A
G
T
P
P
Cat
Felis silvestris
Mouse
Mus musculus
Q80UP3
929
104029
Y739
R
A
Q
E
H
L
N
Y
V
T
E
I
A
Q
D
Rat
Rattus norvegicus
O08560
929
103991
Y739
R
A
Q
E
H
L
N
Y
V
T
E
I
A
Q
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513139
955
107141
A750
L
D
P
D
M
V
V
A
Q
Q
G
G
T
S
P
Chicken
Gallus gallus
XP_416357
1074
118933
S868
L
D
P
E
L
V
M
S
Q
Q
G
G
T
P
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001922445
1086
121319
P865
S
P
P
N
T
P
G
P
R
V
A
E
L
Q
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q09103
1457
160124
D1255
I
D
E
L
Y
I
L
D
H
E
A
A
T
M
P
Honey Bee
Apis mellifera
XP_396522
837
92900
K647
D
T
T
Q
R
R
E
K
R
A
A
Q
R
R
A
Nematode Worm
Caenorhab. elegans
Q10024
937
105180
E747
K
V
P
M
L
K
R
E
K
K
T
P
C
T
P
Sea Urchin
Strong. purpuratus
XP_796061
815
92455
S625
E
P
C
R
L
P
P
S
I
I
H
I
M
L
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.4
86.4
N.A.
55.5
56.6
N.A.
75.4
80.7
N.A.
56.6
N.A.
31.6
34.1
34
43.3
Protein Similarity:
100
99.9
99.6
89.1
N.A.
69.3
69.3
N.A.
80.9
86.4
N.A.
69.1
N.A.
44.5
49.4
49.6
55.9
P-Site Identity:
100
100
100
86.6
N.A.
0
0
N.A.
73.3
66.6
N.A.
13.3
N.A.
26.6
6.6
13.3
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
13.3
13.3
N.A.
80
86.6
N.A.
26.6
N.A.
46.6
13.3
26.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
0
0
0
0
0
8
0
8
54
8
16
0
8
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
8
54
0
39
0
0
0
8
0
0
0
0
0
0
16
% D
% Glu:
8
0
8
24
0
0
8
8
0
8
16
8
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
8
0
0
0
16
47
0
0
0
% G
% His:
0
0
0
0
16
0
0
0
8
0
8
0
0
0
0
% H
% Ile:
8
0
0
0
0
8
0
0
8
8
0
24
0
0
0
% I
% Lys:
8
0
0
0
0
8
0
8
8
8
0
0
0
0
0
% K
% Leu:
47
0
0
8
24
16
16
0
0
0
0
0
8
8
0
% L
% Met:
0
0
0
8
39
0
8
0
0
0
0
0
8
8
0
% M
% Asn:
0
0
0
8
0
0
16
0
0
0
0
0
0
0
0
% N
% Pro:
0
16
62
0
0
16
8
8
0
24
0
8
0
39
62
% P
% Gln:
0
0
16
8
0
0
0
0
47
24
0
8
0
24
0
% Q
% Arg:
16
0
0
8
8
8
8
0
16
0
0
0
8
8
16
% R
% Ser:
8
0
0
0
0
0
0
47
0
0
0
0
0
8
0
% S
% Thr:
0
8
8
0
8
0
0
0
0
16
8
0
54
8
0
% T
% Val:
0
8
0
0
0
47
31
0
16
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
16
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _