KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DGKI
All Species:
21.21
Human Site:
S951
Identified Species:
38.89
UniProt:
O75912
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75912
NP_004708.1
1065
116997
S951
E
S
Y
K
N
G
G
S
L
L
I
Q
G
P
D
Chimpanzee
Pan troglodytes
XP_001147695
1066
117064
S952
E
S
Y
K
N
G
G
S
L
L
I
Q
G
P
D
Rhesus Macaque
Macaca mulatta
XP_001107030
1066
117055
S952
E
S
Y
K
N
G
G
S
L
L
I
Q
G
P
D
Dog
Lupus familis
XP_539825
1017
113427
S903
E
S
Y
K
N
G
G
S
L
L
I
Q
G
P
D
Cat
Felis silvestris
Mouse
Mus musculus
Q80UP3
929
104029
R825
M
H
R
D
Q
K
S
R
T
L
L
H
H
A
V
Rat
Rattus norvegicus
O08560
929
103991
R825
M
H
R
D
H
Q
S
R
T
L
L
H
H
A
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513139
955
107141
S841
E
C
C
R
N
G
G
S
L
S
I
R
G
P
D
Chicken
Gallus gallus
XP_416357
1074
118933
N960
E
C
C
K
K
G
A
N
L
L
I
Q
G
P
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001922445
1086
121319
D957
E
L
H
K
K
G
A
D
L
C
V
Q
D
P
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q09103
1457
160124
S1346
A
L
H
E
Q
G
Y
S
L
Q
S
V
N
K
N
Honey Bee
Apis mellifera
XP_396522
837
92900
Q733
L
S
I
D
S
T
G
Q
T
A
L
H
L
A
S
Nematode Worm
Caenorhab. elegans
Q10024
937
105180
S833
R
L
L
V
E
H
N
S
L
P
Y
E
P
D
K
Sea Urchin
Strong. purpuratus
XP_796061
815
92455
T711
R
K
G
A
N
L
E
T
M
D
Q
H
G
M
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.4
86.4
N.A.
55.5
56.6
N.A.
75.4
80.7
N.A.
56.6
N.A.
31.6
34.1
34
43.3
Protein Similarity:
100
99.9
99.6
89.1
N.A.
69.3
69.3
N.A.
80.9
86.4
N.A.
69.1
N.A.
44.5
49.4
49.6
55.9
P-Site Identity:
100
100
100
100
N.A.
6.6
6.6
N.A.
66.6
66.6
N.A.
40
N.A.
20
13.3
13.3
13.3
P-Site Similarity:
100
100
100
100
N.A.
13.3
20
N.A.
80
73.3
N.A.
53.3
N.A.
40
26.6
20
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
0
0
16
0
0
8
0
0
0
24
8
% A
% Cys:
0
16
16
0
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
0
0
0
24
0
0
0
8
0
8
0
0
8
8
47
% D
% Glu:
54
0
0
8
8
0
8
0
0
0
0
8
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
0
0
62
47
0
0
0
0
0
54
0
0
% G
% His:
0
16
16
0
8
8
0
0
0
0
0
31
16
0
0
% H
% Ile:
0
0
8
0
0
0
0
0
0
0
47
0
0
0
0
% I
% Lys:
0
8
0
47
16
8
0
0
0
0
0
0
0
8
8
% K
% Leu:
8
24
8
0
0
8
0
0
70
54
24
0
8
0
0
% L
% Met:
16
0
0
0
0
0
0
0
8
0
0
0
0
8
0
% M
% Asn:
0
0
0
0
47
0
8
8
0
0
0
0
8
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
8
0
0
8
54
0
% P
% Gln:
0
0
0
0
16
8
0
8
0
8
8
47
0
0
0
% Q
% Arg:
16
0
16
8
0
0
0
16
0
0
0
8
0
0
0
% R
% Ser:
0
39
0
0
8
0
16
54
0
8
8
0
0
0
8
% S
% Thr:
0
0
0
0
0
8
0
8
24
0
0
0
0
0
8
% T
% Val:
0
0
0
8
0
0
0
0
0
0
8
8
0
0
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
31
0
0
0
8
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _