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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DGKI
All Species:
23.03
Human Site:
T594
Identified Species:
42.22
UniProt:
O75912
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75912
NP_004708.1
1065
116997
T594
V
C
D
G
T
D
L
T
P
K
I
Q
E
L
K
Chimpanzee
Pan troglodytes
XP_001147695
1066
117064
T595
V
C
D
G
T
D
L
T
P
K
I
Q
E
L
K
Rhesus Macaque
Macaca mulatta
XP_001107030
1066
117055
T595
V
C
D
G
T
D
L
T
P
K
I
Q
E
L
K
Dog
Lupus familis
XP_539825
1017
113427
T554
V
C
D
G
T
D
L
T
P
K
I
Q
E
L
K
Cat
Felis silvestris
Mouse
Mus musculus
Q80UP3
929
104029
D500
F
L
M
G
S
S
K
D
L
A
K
H
I
R
V
Rat
Rattus norvegicus
O08560
929
103991
D500
F
L
M
G
S
S
K
D
L
A
K
H
I
R
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513139
955
107141
Q509
E
H
R
D
F
E
P
Q
R
H
D
D
G
Y
I
Chicken
Gallus gallus
XP_416357
1074
118933
T595
V
C
D
G
T
D
L
T
P
K
I
Q
E
L
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001922445
1086
121319
T582
V
C
D
G
T
D
L
T
S
K
V
Q
D
L
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q09103
1457
160124
I1011
Q
M
G
G
K
D
L
I
L
R
Q
Y
R
N
L
Honey Bee
Apis mellifera
XP_396522
837
92900
H408
L
T
P
K
L
K
E
H
R
V
H
A
I
V
F
Nematode Worm
Caenorhab. elegans
Q10024
937
105180
T507
M
A
I
M
P
L
G
T
G
N
D
L
A
R
C
Sea Urchin
Strong. purpuratus
XP_796061
815
92455
K386
L
S
E
I
D
K
L
K
F
K
P
M
P
P
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.4
86.4
N.A.
55.5
56.6
N.A.
75.4
80.7
N.A.
56.6
N.A.
31.6
34.1
34
43.3
Protein Similarity:
100
99.9
99.6
89.1
N.A.
69.3
69.3
N.A.
80.9
86.4
N.A.
69.1
N.A.
44.5
49.4
49.6
55.9
P-Site Identity:
100
100
100
100
N.A.
6.6
6.6
N.A.
0
100
N.A.
80
N.A.
20
0
6.6
13.3
P-Site Similarity:
100
100
100
100
N.A.
13.3
13.3
N.A.
6.6
100
N.A.
93.3
N.A.
26.6
13.3
13.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
0
0
0
16
0
8
8
0
0
% A
% Cys:
0
47
0
0
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
0
0
47
8
8
54
0
16
0
0
16
8
8
0
0
% D
% Glu:
8
0
8
0
0
8
8
0
0
0
0
0
39
0
0
% E
% Phe:
16
0
0
0
8
0
0
0
8
0
0
0
0
0
8
% F
% Gly:
0
0
8
70
0
0
8
0
8
0
0
0
8
0
0
% G
% His:
0
8
0
0
0
0
0
8
0
8
8
16
0
0
0
% H
% Ile:
0
0
8
8
0
0
0
8
0
0
39
0
24
0
8
% I
% Lys:
0
0
0
8
8
16
16
8
0
54
16
0
0
0
47
% K
% Leu:
16
16
0
0
8
8
62
0
24
0
0
8
0
47
8
% L
% Met:
8
8
16
8
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
8
0
0
0
8
0
% N
% Pro:
0
0
8
0
8
0
8
0
39
0
8
0
8
8
0
% P
% Gln:
8
0
0
0
0
0
0
8
0
0
8
47
0
0
0
% Q
% Arg:
0
0
8
0
0
0
0
0
16
8
0
0
8
24
0
% R
% Ser:
0
8
0
0
16
16
0
0
8
0
0
0
0
0
0
% S
% Thr:
0
8
0
0
47
0
0
54
0
0
0
0
0
0
0
% T
% Val:
47
0
0
0
0
0
0
0
0
8
8
0
0
8
24
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
8
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _