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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DGKI
All Species:
17.88
Human Site:
Y965
Identified Species:
32.78
UniProt:
O75912
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75912
NP_004708.1
1065
116997
Y965
D
H
C
S
L
L
H
Y
A
A
K
T
G
N
G
Chimpanzee
Pan troglodytes
XP_001147695
1066
117064
Y966
D
H
C
S
L
L
H
Y
A
A
K
T
G
N
G
Rhesus Macaque
Macaca mulatta
XP_001107030
1066
117055
Y966
D
H
C
S
L
L
H
Y
A
A
K
T
G
N
G
Dog
Lupus familis
XP_539825
1017
113427
H917
D
H
C
S
L
L
H
H
A
A
K
T
G
H
G
Cat
Felis silvestris
Mouse
Mus musculus
Q80UP3
929
104029
V839
V
S
T
G
S
K
E
V
V
R
Y
L
L
D
H
Rat
Rattus norvegicus
O08560
929
103991
V839
V
S
T
G
S
K
E
V
V
R
Y
L
L
D
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513139
955
107141
Y855
D
H
C
S
L
L
H
Y
A
A
Q
T
G
N
G
Chicken
Gallus gallus
XP_416357
1074
118933
H974
D
H
G
S
L
L
H
H
A
A
K
S
G
H
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001922445
1086
121319
Y971
A
G
R
T
L
L
H
Y
A
V
E
V
G
S
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q09103
1457
160124
F1360
N
G
Q
T
A
L
H
F
A
C
K
Y
N
H
R
Honey Bee
Apis mellifera
XP_396522
837
92900
I747
S
R
Y
G
H
K
N
I
V
R
Y
L
I
A
C
Nematode Worm
Caenorhab. elegans
Q10024
937
105180
Y847
K
N
W
R
F
L
D
Y
V
S
N
A
E
E
G
Sea Urchin
Strong. purpuratus
XP_796061
815
92455
R725
T
S
L
H
H
A
A
R
F
G
H
K
E
I
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.4
86.4
N.A.
55.5
56.6
N.A.
75.4
80.7
N.A.
56.6
N.A.
31.6
34.1
34
43.3
Protein Similarity:
100
99.9
99.6
89.1
N.A.
69.3
69.3
N.A.
80.9
86.4
N.A.
69.1
N.A.
44.5
49.4
49.6
55.9
P-Site Identity:
100
100
100
86.6
N.A.
0
0
N.A.
93.3
73.3
N.A.
40
N.A.
26.6
0
20
0
P-Site Similarity:
100
100
100
100
N.A.
6.6
6.6
N.A.
100
93.3
N.A.
60
N.A.
53.3
6.6
33.3
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
8
8
8
0
62
47
0
8
0
8
0
% A
% Cys:
0
0
39
0
0
0
0
0
0
8
0
0
0
0
8
% C
% Asp:
47
0
0
0
0
0
8
0
0
0
0
0
0
16
0
% D
% Glu:
0
0
0
0
0
0
16
0
0
0
8
0
16
8
0
% E
% Phe:
0
0
0
0
8
0
0
8
8
0
0
0
0
0
0
% F
% Gly:
0
16
8
24
0
0
0
0
0
8
0
0
54
0
54
% G
% His:
0
47
0
8
16
0
62
16
0
0
8
0
0
24
16
% H
% Ile:
0
0
0
0
0
0
0
8
0
0
0
0
8
8
0
% I
% Lys:
8
0
0
0
0
24
0
0
0
0
47
8
0
0
8
% K
% Leu:
0
0
8
0
54
70
0
0
0
0
0
24
16
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
8
0
0
0
0
8
0
0
0
8
0
8
31
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
8
0
0
0
0
0
0
0
8
0
0
0
0
% Q
% Arg:
0
8
8
8
0
0
0
8
0
24
0
0
0
0
8
% R
% Ser:
8
24
0
47
16
0
0
0
0
8
0
8
0
8
0
% S
% Thr:
8
0
16
16
0
0
0
0
0
0
0
39
0
0
0
% T
% Val:
16
0
0
0
0
0
0
16
31
8
0
8
0
0
8
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
47
0
0
24
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _