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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PAK3
All Species:
26.36
Human Site:
S186
Identified Species:
48.33
UniProt:
O75914
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75914
NP_001121638.1
559
62310
S186
P
P
L
A
P
P
V
S
E
E
E
D
E
E
E
Chimpanzee
Pan troglodytes
NP_001009039
559
62291
S186
P
P
L
A
P
P
V
S
E
E
E
D
E
E
E
Rhesus Macaque
Macaca mulatta
XP_001100151
563
62483
S186
P
P
L
A
P
P
V
S
E
E
E
D
E
E
E
Dog
Lupus familis
XP_851348
559
62265
S186
P
P
L
A
P
P
V
S
E
E
E
D
E
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q61036
559
62379
S186
P
P
L
A
P
P
V
S
E
E
E
D
E
E
E
Rat
Rattus norvegicus
Q62829
544
60692
E177
V
S
E
E
E
D
E
E
E
E
E
E
E
D
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_420314
543
60608
E177
V
S
E
E
E
D
E
E
D
E
E
E
E
D
D
Frog
Xenopus laevis
NP_001079232
564
62749
S186
P
P
L
A
P
P
V
S
E
E
E
D
E
E
E
Zebra Danio
Brachydanio rerio
NP_958485
577
63243
P209
R
S
V
I
E
P
L
P
P
P
L
S
T
K
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VXE5
639
69601
S272
Y
P
P
M
Y
P
T
S
H
Q
Q
Q
Q
Q
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q17850
572
63863
N189
S
T
S
S
A
G
Y
N
S
K
Q
G
V
P
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03497
939
102344
S437
N
K
F
P
P
S
T
S
D
S
H
N
Y
G
S
Red Bread Mold
Neurospora crassa
Q7RZD3
954
103773
L580
T
A
A
Y
Q
Q
Q
L
L
Q
H
Q
Q
E
Q
Conservation
Percent
Protein Identity:
100
100
93.7
99.1
N.A.
98.5
96
N.A.
N.A.
93.5
93.7
78.1
N.A.
33
N.A.
50.8
N.A.
Protein Similarity:
100
100
95.9
99.4
N.A.
99.1
96.5
N.A.
N.A.
95.1
95.9
83.3
N.A.
50.8
N.A.
65
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
26.6
N.A.
N.A.
20
100
6.6
N.A.
20
N.A.
0
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
46.6
N.A.
N.A.
46.6
100
33.3
N.A.
53.3
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
31.6
30.9
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.2
44
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
47
8
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
16
0
0
16
0
0
47
0
16
24
% D
% Glu:
0
0
16
16
24
0
16
16
54
62
62
16
62
54
47
% E
% Phe:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
8
0
0
0
0
0
8
0
8
0
% G
% His:
0
0
0
0
0
0
0
0
8
0
16
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
8
0
0
0
0
0
0
0
8
0
0
0
8
0
% K
% Leu:
0
0
47
0
0
0
8
8
8
0
8
0
0
0
0
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
0
0
8
0
0
0
8
0
0
0
% N
% Pro:
47
54
8
8
54
62
0
8
8
8
0
0
0
8
8
% P
% Gln:
0
0
0
0
8
8
8
0
0
16
16
16
16
8
16
% Q
% Arg:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
8
24
8
8
0
8
0
62
8
8
0
8
0
0
8
% S
% Thr:
8
8
0
0
0
0
16
0
0
0
0
0
8
0
0
% T
% Val:
16
0
8
0
0
0
47
0
0
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
8
8
0
8
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _