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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PAK3
All Species:
22.42
Human Site:
S227
Identified Species:
41.11
UniProt:
O75914
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75914
NP_001121638.1
559
62310
S227
S
V
V
E
S
I
A
S
P
A
V
P
N
K
E
Chimpanzee
Pan troglodytes
NP_001009039
559
62291
S227
S
V
V
E
S
I
A
S
P
A
V
P
N
K
E
Rhesus Macaque
Macaca mulatta
XP_001100151
563
62483
S227
S
V
V
E
S
I
A
S
P
A
A
P
N
K
E
Dog
Lupus familis
XP_851348
559
62265
S227
S
V
L
E
S
I
A
S
P
A
A
P
N
K
E
Cat
Felis silvestris
Mouse
Mus musculus
Q61036
559
62379
S227
S
V
V
E
S
I
A
S
P
A
A
P
N
K
E
Rat
Rattus norvegicus
Q62829
544
60692
S212
S
V
V
E
S
I
A
S
P
A
A
P
N
K
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_420314
543
60608
A211
R
S
V
I
E
P
V
A
A
P
A
P
A
K
E
Frog
Xenopus laevis
NP_001079232
564
62749
K232
V
A
L
T
A
P
A
K
E
A
S
T
S
P
V
Zebra Danio
Brachydanio rerio
NP_958485
577
63243
T246
N
T
N
T
T
N
T
T
N
T
T
N
T
T
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VXE5
639
69601
A312
H
Q
H
L
A
K
S
A
S
R
A
S
S
S
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q17850
572
63863
L239
P
D
R
P
A
R
T
L
S
I
Y
T
K
P
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03497
939
102344
K564
Q
Q
V
A
Q
S
P
K
A
P
A
Q
E
T
V
Red Bread Mold
Neurospora crassa
Q7RZD3
954
103773
Q618
T
P
P
T
S
Q
H
Q
H
P
R
Q
P
D
I
Conservation
Percent
Protein Identity:
100
100
93.7
99.1
N.A.
98.5
96
N.A.
N.A.
93.5
93.7
78.1
N.A.
33
N.A.
50.8
N.A.
Protein Similarity:
100
100
95.9
99.4
N.A.
99.1
96.5
N.A.
N.A.
95.1
95.9
83.3
N.A.
50.8
N.A.
65
N.A.
P-Site Identity:
100
100
93.3
86.6
N.A.
93.3
93.3
N.A.
N.A.
26.6
13.3
0
N.A.
0
N.A.
0
N.A.
P-Site Similarity:
100
100
93.3
93.3
N.A.
93.3
93.3
N.A.
N.A.
33.3
33.3
20
N.A.
26.6
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
31.6
30.9
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.2
44
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
8
24
0
54
16
16
54
54
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
0
0
0
0
0
0
0
0
8
0
% D
% Glu:
0
0
0
47
8
0
0
0
8
0
0
0
8
0
54
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
8
0
8
0
0
0
8
0
8
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
47
0
0
0
8
0
0
0
0
8
% I
% Lys:
0
0
0
0
0
8
0
16
0
0
0
0
8
54
8
% K
% Leu:
0
0
16
8
0
0
0
8
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
8
0
0
8
0
0
8
0
0
8
47
0
8
% N
% Pro:
8
8
8
8
0
16
8
0
47
24
0
54
8
16
0
% P
% Gln:
8
16
0
0
8
8
0
8
0
0
0
16
0
0
0
% Q
% Arg:
8
0
8
0
0
8
0
0
0
8
8
0
0
0
0
% R
% Ser:
47
8
0
0
54
8
8
47
16
0
8
8
16
8
8
% S
% Thr:
8
8
0
24
8
0
16
8
0
8
8
16
8
16
0
% T
% Val:
8
47
54
0
0
0
8
0
0
0
16
0
0
0
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _