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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PAK3 All Species: 21.82
Human Site: S98 Identified Species: 40
UniProt: O75914 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75914 NP_001121638.1 559 62310 S98 F T P D L Y G S Q M C P G K L
Chimpanzee Pan troglodytes NP_001009039 559 62291 S98 F T P D L Y G S Q M C P G K L
Rhesus Macaque Macaca mulatta XP_001100151 563 62483 S98 F T P D L Y G S Q M C P G K L
Dog Lupus familis XP_851348 559 62265 S98 F T P D L Y G S Q M C P G K L
Cat Felis silvestris
Mouse Mus musculus Q61036 559 62379 S98 F T P D L Y G S Q M C P G K L
Rat Rattus norvegicus Q62829 544 60692 W98 F T G I P E Q W A R L L Q T S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_420314 543 60608 W98 F T G I P E Q W A R L L Q T S
Frog Xenopus laevis NP_001079232 564 62749 S98 F T P D L C G S Q M G T G K L
Zebra Danio Brachydanio rerio NP_958485 577 63243 W102 F T G M P E Q W A R L L Q T S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VXE5 639 69601 P119 H P M M S H G P G M M M P P E
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q17850 572 63863 W95 F T G M P E A W A R L L T D S
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q03497 939 102344 I309 F T S F V Q N I K R N S Q D D
Red Bread Mold Neurospora crassa Q7RZD3 954 103773 W362 F T G L P K E W Q R L I S E S
Conservation
Percent
Protein Identity: 100 100 93.7 99.1 N.A. 98.5 96 N.A. N.A. 93.5 93.7 78.1 N.A. 33 N.A. 50.8 N.A.
Protein Similarity: 100 100 95.9 99.4 N.A. 99.1 96.5 N.A. N.A. 95.1 95.9 83.3 N.A. 50.8 N.A. 65 N.A.
P-Site Identity: 100 100 100 100 N.A. 100 13.3 N.A. N.A. 13.3 80 13.3 N.A. 13.3 N.A. 13.3 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 13.3 N.A. N.A. 13.3 80 13.3 N.A. 20 N.A. 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 31.6 30.9
Protein Similarity: N.A. N.A. N.A. N.A. 43.2 44
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 20
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 8 0 31 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 8 0 0 0 0 39 0 0 0 0 % C
% Asp: 0 0 0 47 0 0 0 0 0 0 0 0 0 16 8 % D
% Glu: 0 0 0 0 0 31 8 0 0 0 0 0 0 8 8 % E
% Phe: 93 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 39 0 0 0 54 0 8 0 8 0 47 0 0 % G
% His: 8 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 16 0 0 0 8 0 0 0 8 0 0 0 % I
% Lys: 0 0 0 0 0 8 0 0 8 0 0 0 0 47 0 % K
% Leu: 0 0 0 8 47 0 0 0 0 0 39 31 0 0 47 % L
% Met: 0 0 8 24 0 0 0 0 0 54 8 8 0 0 0 % M
% Asn: 0 0 0 0 0 0 8 0 0 0 8 0 0 0 0 % N
% Pro: 0 8 47 0 39 0 0 8 0 0 0 39 8 8 0 % P
% Gln: 0 0 0 0 0 8 24 0 54 0 0 0 31 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 47 0 0 0 0 0 % R
% Ser: 0 0 8 0 8 0 0 47 0 0 0 8 8 0 39 % S
% Thr: 0 93 0 0 0 0 0 0 0 0 0 8 8 24 0 % T
% Val: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 39 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 39 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _