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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PAK3
All Species:
31.82
Human Site:
T59
Identified Species:
58.33
UniProt:
O75914
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75914
NP_001121638.1
559
62310
T59
F
P
G
G
G
D
K
T
N
K
K
K
E
K
E
Chimpanzee
Pan troglodytes
NP_001009039
559
62291
T59
F
P
G
G
G
D
K
T
N
K
K
K
E
K
E
Rhesus Macaque
Macaca mulatta
XP_001100151
563
62483
T59
F
P
G
G
G
D
K
T
N
K
K
K
E
K
E
Dog
Lupus familis
XP_851348
559
62265
T59
F
P
G
G
G
D
K
T
N
K
K
K
E
K
E
Cat
Felis silvestris
Mouse
Mus musculus
Q61036
559
62379
T59
F
P
G
G
G
D
K
T
N
K
K
K
E
K
E
Rat
Rattus norvegicus
Q62829
544
60692
T59
F
P
G
G
G
D
K
T
N
K
K
K
E
K
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_420314
543
60608
T59
F
P
G
G
G
D
K
T
N
K
K
K
E
K
E
Frog
Xenopus laevis
NP_001079232
564
62749
T59
F
P
G
G
G
D
K
T
N
K
K
K
E
K
E
Zebra Danio
Brachydanio rerio
NP_958485
577
63243
D63
S
I
L
T
G
G
G
D
K
T
N
K
K
K
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VXE5
639
69601
H80
K
T
I
V
R
P
H
H
N
N
N
K
A
D
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q17850
572
63863
K56
N
P
F
M
K
K
N
K
D
K
K
E
A
S
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03497
939
102344
P270
N
P
L
K
N
S
S
P
P
K
K
Q
T
E
K
Red Bread Mold
Neurospora crassa
Q7RZD3
954
103773
N323
S
G
F
S
G
F
M
N
S
L
V
G
S
P
K
Conservation
Percent
Protein Identity:
100
100
93.7
99.1
N.A.
98.5
96
N.A.
N.A.
93.5
93.7
78.1
N.A.
33
N.A.
50.8
N.A.
Protein Similarity:
100
100
95.9
99.4
N.A.
99.1
96.5
N.A.
N.A.
95.1
95.9
83.3
N.A.
50.8
N.A.
65
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
100
26.6
N.A.
13.3
N.A.
26.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
100
33.3
N.A.
13.3
N.A.
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
31.6
30.9
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.2
44
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
16
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
62
0
8
8
0
0
0
0
8
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
8
62
8
77
% E
% Phe:
62
0
16
0
0
8
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
62
62
77
8
8
0
0
0
0
8
0
0
0
% G
% His:
0
0
0
0
0
0
8
8
0
0
0
0
0
0
0
% H
% Ile:
0
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
8
0
0
8
8
8
62
8
8
77
77
77
8
70
16
% K
% Leu:
0
0
16
0
0
0
0
0
0
8
0
0
0
0
0
% L
% Met:
0
0
0
8
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
16
0
0
0
8
0
8
8
70
8
16
0
0
0
0
% N
% Pro:
0
77
0
0
0
8
0
8
8
0
0
0
0
8
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% Q
% Arg:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
16
0
0
8
0
8
8
0
8
0
0
0
8
8
0
% S
% Thr:
0
8
0
8
0
0
0
62
0
8
0
0
8
0
8
% T
% Val:
0
0
0
8
0
0
0
0
0
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _