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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PAK3 All Species: 35.45
Human Site: T92 Identified Species: 65
UniProt: O75914 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75914 NP_001121638.1 559 62310 T92 D A V T G E F T P D L Y G S Q
Chimpanzee Pan troglodytes NP_001009039 559 62291 T92 D A V T G E F T P D L Y G S Q
Rhesus Macaque Macaca mulatta XP_001100151 563 62483 T92 D A V T G E F T P D L Y G S Q
Dog Lupus familis XP_851348 559 62265 T92 D A V T G E F T P D L Y G S Q
Cat Felis silvestris
Mouse Mus musculus Q61036 559 62379 T92 D A V T G E F T P D L Y G S Q
Rat Rattus norvegicus Q62829 544 60692 T92 D A V T G E F T G I P E Q W A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_420314 543 60608 T92 D A V T G E F T G I P E Q W A
Frog Xenopus laevis NP_001079232 564 62749 T92 D A V T G E F T P D L C G S Q
Zebra Danio Brachydanio rerio NP_958485 577 63243 T96 D A V T G E F T G M P E Q W A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VXE5 639 69601 P113 P M A P G A H P M M S H G P G
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q17850 572 63863 T89 D P K T G E F T G M P E A W A
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q03497 939 102344 T303 L R M K D V F T S F V Q N I K
Red Bread Mold Neurospora crassa Q7RZD3 954 103773 T356 D S N T G Q F T G L P K E W Q
Conservation
Percent
Protein Identity: 100 100 93.7 99.1 N.A. 98.5 96 N.A. N.A. 93.5 93.7 78.1 N.A. 33 N.A. 50.8 N.A.
Protein Similarity: 100 100 95.9 99.4 N.A. 99.1 96.5 N.A. N.A. 95.1 95.9 83.3 N.A. 50.8 N.A. 65 N.A.
P-Site Identity: 100 100 100 100 N.A. 100 53.3 N.A. N.A. 53.3 93.3 53.3 N.A. 13.3 N.A. 40 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 53.3 N.A. N.A. 53.3 93.3 53.3 N.A. 20 N.A. 40 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 31.6 30.9
Protein Similarity: N.A. N.A. N.A. N.A. 43.2 44
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 40
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 53.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 70 8 0 0 8 0 0 0 0 0 0 8 0 31 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % C
% Asp: 85 0 0 0 8 0 0 0 0 47 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 77 0 0 0 0 0 31 8 0 0 % E
% Phe: 0 0 0 0 0 0 93 0 0 8 0 0 0 0 0 % F
% Gly: 0 0 0 0 93 0 0 0 39 0 0 0 54 0 8 % G
% His: 0 0 0 0 0 0 8 0 0 0 0 8 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 16 0 0 0 8 0 % I
% Lys: 0 0 8 8 0 0 0 0 0 0 0 8 0 0 8 % K
% Leu: 8 0 0 0 0 0 0 0 0 8 47 0 0 0 0 % L
% Met: 0 8 8 0 0 0 0 0 8 24 0 0 0 0 0 % M
% Asn: 0 0 8 0 0 0 0 0 0 0 0 0 8 0 0 % N
% Pro: 8 8 0 8 0 0 0 8 47 0 39 0 0 8 0 % P
% Gln: 0 0 0 0 0 8 0 0 0 0 0 8 24 0 54 % Q
% Arg: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 8 0 0 0 0 0 0 8 0 8 0 0 47 0 % S
% Thr: 0 0 0 85 0 0 0 93 0 0 0 0 0 0 0 % T
% Val: 0 0 70 0 0 8 0 0 0 0 8 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 39 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 39 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _