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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PAK3
All Species:
24.85
Human Site:
Y152
Identified Species:
45.56
UniProt:
O75914
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75914
NP_001121638.1
559
62310
Y152
E
T
V
N
N
Q
K
Y
M
S
F
T
S
G
D
Chimpanzee
Pan troglodytes
NP_001009039
559
62291
Y152
E
T
V
N
N
Q
K
Y
M
S
F
T
S
G
D
Rhesus Macaque
Macaca mulatta
XP_001100151
563
62483
Y152
E
T
V
N
N
Q
K
Y
M
S
F
T
S
G
D
Dog
Lupus familis
XP_851348
559
62265
Y152
E
T
V
N
N
Q
K
Y
M
S
F
T
S
G
D
Cat
Felis silvestris
Mouse
Mus musculus
Q61036
559
62379
Y152
E
T
V
N
N
Q
K
Y
M
S
F
T
S
G
D
Rat
Rattus norvegicus
Q62829
544
60692
G143
K
Y
M
S
F
T
S
G
D
K
S
A
H
G
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_420314
543
60608
G143
K
Y
M
S
F
T
S
G
D
K
S
A
H
G
Y
Frog
Xenopus laevis
NP_001079232
564
62749
Y152
E
T
V
N
N
Q
K
Y
M
S
F
T
S
G
D
Zebra Danio
Brachydanio rerio
NP_958485
577
63243
D175
A
V
A
T
V
S
E
D
E
D
E
E
E
D
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VXE5
639
69601
Q238
G
S
M
P
Q
Q
Q
Q
T
S
P
V
G
S
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q17850
572
63863
P155
T
P
S
Y
G
L
K
P
Q
P
Y
S
T
S
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03497
939
102344
D403
V
T
E
T
N
G
E
D
K
M
F
K
T
F
N
Red Bread Mold
Neurospora crassa
Q7RZD3
954
103773
S546
E
H
R
N
R
S
R
S
N
S
R
T
N
G
A
Conservation
Percent
Protein Identity:
100
100
93.7
99.1
N.A.
98.5
96
N.A.
N.A.
93.5
93.7
78.1
N.A.
33
N.A.
50.8
N.A.
Protein Similarity:
100
100
95.9
99.4
N.A.
99.1
96.5
N.A.
N.A.
95.1
95.9
83.3
N.A.
50.8
N.A.
65
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
6.6
N.A.
N.A.
6.6
100
0
N.A.
13.3
N.A.
6.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
26.6
N.A.
N.A.
26.6
100
13.3
N.A.
33.3
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
31.6
30.9
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.2
44
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
33.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
0
0
0
0
0
0
0
16
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
16
16
8
0
0
0
8
47
% D
% Glu:
54
0
8
0
0
0
16
0
8
0
8
8
8
0
8
% E
% Phe:
0
0
0
0
16
0
0
0
0
0
54
0
0
8
0
% F
% Gly:
8
0
0
0
8
8
0
16
0
0
0
0
8
70
0
% G
% His:
0
8
0
0
0
0
0
0
0
0
0
0
16
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
16
0
0
0
0
0
54
0
8
16
0
8
0
0
0
% K
% Leu:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
24
0
0
0
0
0
47
8
0
0
0
0
0
% M
% Asn:
0
0
0
54
54
0
0
0
8
0
0
0
8
0
8
% N
% Pro:
0
8
0
8
0
0
0
8
0
8
8
0
0
0
0
% P
% Gln:
0
0
0
0
8
54
8
8
8
0
0
0
0
0
0
% Q
% Arg:
0
0
8
0
8
0
8
0
0
0
8
0
0
0
0
% R
% Ser:
0
8
8
16
0
16
16
8
0
62
16
8
47
16
8
% S
% Thr:
8
54
0
16
0
16
0
0
8
0
0
54
16
0
0
% T
% Val:
8
8
47
0
8
0
0
0
0
0
0
8
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
16
0
8
0
0
0
47
0
0
8
0
0
0
16
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _