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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RGS9
All Species:
6.97
Human Site:
S258
Identified Species:
17.04
UniProt:
O75916
Number Species:
9
Phosphosite Substitution
Charge Score:
0.44
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75916
NP_001075424.1
674
76966
S258
V
K
Y
S
E
Q
F
S
S
N
D
A
I
M
S
Chimpanzee
Pan troglodytes
XP_511633
674
76928
S258
V
K
Y
S
E
Q
F
S
S
N
D
A
I
M
S
Rhesus Macaque
Macaca mulatta
XP_001083719
446
50768
Q42
D
V
V
Q
W
L
T
Q
K
F
C
I
S
E
E
Dog
Lupus familis
XP_548024
677
76804
L258
V
K
Y
S
E
Q
F
L
S
N
D
A
I
M
S
Cat
Felis silvestris
Mouse
Mus musculus
O54828
675
76954
D258
S
E
Q
F
S
S
N
D
A
I
M
S
G
C
L
Rat
Rattus norvegicus
P49805
677
77113
D258
S
E
Q
F
S
S
N
D
A
I
M
S
G
C
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509970
763
86274
A258
V
K
Y
S
E
Q
F
A
S
N
D
P
F
I
S
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_573328
1244
134097
S457
V
C
Y
S
E
T
F
S
E
Y
D
F
F
L
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P49809
555
63260
E151
E
L
E
D
F
E
A
E
N
L
A
K
L
Q
K
Sea Urchin
Strong. purpuratus
XP_787995
542
62633
E138
N
K
Q
N
F
G
L
E
E
Y
E
N
T
A
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
37.8
89.3
N.A.
90.5
90.2
N.A.
66.7
N.A.
N.A.
N.A.
N.A.
24.1
N.A.
23.2
35.6
Protein Similarity:
100
99.8
50.4
93.5
N.A.
93.9
94
N.A.
75.6
N.A.
N.A.
N.A.
N.A.
35.2
N.A.
40.3
52.3
P-Site Identity:
100
100
0
93.3
N.A.
0
0
N.A.
73.3
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
0
6.6
P-Site Similarity:
100
100
0
93.3
N.A.
20
20
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
53.3
N.A.
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
10
10
20
0
10
30
0
10
0
% A
% Cys:
0
10
0
0
0
0
0
0
0
0
10
0
0
20
0
% C
% Asp:
10
0
0
10
0
0
0
20
0
0
50
0
0
0
0
% D
% Glu:
10
20
10
0
50
10
0
20
20
0
10
0
0
10
10
% E
% Phe:
0
0
0
20
20
0
50
0
0
10
0
10
20
0
0
% F
% Gly:
0
0
0
0
0
10
0
0
0
0
0
0
20
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
20
0
10
30
10
0
% I
% Lys:
0
50
0
0
0
0
0
0
10
0
0
10
0
0
10
% K
% Leu:
0
10
0
0
0
10
10
10
0
10
0
0
10
10
20
% L
% Met:
0
0
0
0
0
0
0
0
0
0
20
0
0
30
0
% M
% Asn:
10
0
0
10
0
0
20
0
10
40
0
10
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% P
% Gln:
0
0
30
10
0
40
0
10
0
0
0
0
0
10
10
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
20
0
0
50
20
20
0
30
40
0
0
20
10
0
40
% S
% Thr:
0
0
0
0
0
10
10
0
0
0
0
0
10
0
0
% T
% Val:
50
10
10
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
50
0
0
0
0
0
0
20
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _