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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RGS9 All Species: 17.27
Human Site: S494 Identified Species: 42.22
UniProt: O75916 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75916 NP_001075424.1 674 76966 S494 C M P P S P S S P F S S S C R
Chimpanzee Pan troglodytes XP_511633 674 76928 S494 C V P P S P S S P F S S S C R
Rhesus Macaque Macaca mulatta XP_001083719 446 50768 P271 N A P T V V A P T K L R V E R
Dog Lupus familis XP_548024 677 76804 S494 C V P P S P S S P F S P S C R
Cat Felis silvestris
Mouse Mus musculus O54828 675 76954 S491 C V P P S P S S P F S P S C R
Rat Rattus norvegicus P49805 677 77113 S491 C V P P S P S S P F S P S C R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509970 763 86274 P568 G T R G P L S P R S P S I S P
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_573328 1244 134097 P853 A G I K R L I P N I P E Q R R
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P49809 555 63260 G380 D P L L T P P G S Q A D P F Q
Sea Urchin Strong. purpuratus XP_787995 542 62633 K367 Q H I F L L M K K D S Y Q R F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 37.8 89.3 N.A. 90.5 90.2 N.A. 66.7 N.A. N.A. N.A. N.A. 24.1 N.A. 23.2 35.6
Protein Similarity: 100 99.8 50.4 93.5 N.A. 93.9 94 N.A. 75.6 N.A. N.A. N.A. N.A. 35.2 N.A. 40.3 52.3
P-Site Identity: 100 93.3 13.3 86.6 N.A. 86.6 86.6 N.A. 13.3 N.A. N.A. N.A. N.A. 6.6 N.A. 6.6 6.6
P-Site Similarity: 100 100 20 93.3 N.A. 93.3 93.3 N.A. 13.3 N.A. N.A. N.A. N.A. 6.6 N.A. 26.6 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 10 0 0 0 0 10 0 0 0 10 0 0 0 0 % A
% Cys: 50 0 0 0 0 0 0 0 0 0 0 0 0 50 0 % C
% Asp: 10 0 0 0 0 0 0 0 0 10 0 10 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 10 0 10 0 % E
% Phe: 0 0 0 10 0 0 0 0 0 50 0 0 0 10 10 % F
% Gly: 10 10 0 10 0 0 0 10 0 0 0 0 0 0 0 % G
% His: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 20 0 0 0 10 0 0 10 0 0 10 0 0 % I
% Lys: 0 0 0 10 0 0 0 10 10 10 0 0 0 0 0 % K
% Leu: 0 0 10 10 10 30 0 0 0 0 10 0 0 0 0 % L
% Met: 0 10 0 0 0 0 10 0 0 0 0 0 0 0 0 % M
% Asn: 10 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % N
% Pro: 0 10 60 50 10 60 10 30 50 0 20 30 10 0 10 % P
% Gln: 10 0 0 0 0 0 0 0 0 10 0 0 20 0 10 % Q
% Arg: 0 0 10 0 10 0 0 0 10 0 0 10 0 20 70 % R
% Ser: 0 0 0 0 50 0 60 50 10 10 60 30 50 10 0 % S
% Thr: 0 10 0 10 10 0 0 0 10 0 0 0 0 0 0 % T
% Val: 0 40 0 0 10 10 0 0 0 0 0 0 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _