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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RGS9
All Species:
16.36
Human Site:
S518
Identified Species:
40
UniProt:
O75916
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75916
NP_001075424.1
674
76966
S518
S
R
F
I
R
R
P
S
T
T
I
C
P
S
P
Chimpanzee
Pan troglodytes
XP_511633
674
76928
S518
S
R
F
I
R
R
P
S
T
T
I
C
P
S
P
Rhesus Macaque
Macaca mulatta
XP_001083719
446
50768
H295
E
D
P
V
G
R
A
H
F
M
D
F
L
G
K
Dog
Lupus familis
XP_548024
677
76804
S518
G
R
F
I
R
R
P
S
S
A
I
C
P
S
P
Cat
Felis silvestris
Mouse
Mus musculus
O54828
675
76954
S515
S
R
F
I
R
R
P
S
I
A
I
C
P
S
P
Rat
Rattus norvegicus
P49805
677
77113
S515
S
R
F
I
R
R
P
S
I
A
I
C
P
S
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509970
763
86274
P592
G
S
S
T
C
P
S
P
I
S
V
A
L
V
S
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_573328
1244
134097
R877
T
P
D
F
Q
L
G
R
T
P
T
T
T
S
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P49809
555
63260
D404
T
V
D
F
W
Q
H
D
K
I
T
G
D
I
Q
Sea Urchin
Strong. purpuratus
XP_787995
542
62633
G391
L
A
R
A
M
Q
N
G
T
K
R
K
F
F
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
37.8
89.3
N.A.
90.5
90.2
N.A.
66.7
N.A.
N.A.
N.A.
N.A.
24.1
N.A.
23.2
35.6
Protein Similarity:
100
99.8
50.4
93.5
N.A.
93.9
94
N.A.
75.6
N.A.
N.A.
N.A.
N.A.
35.2
N.A.
40.3
52.3
P-Site Identity:
100
100
6.6
80
N.A.
86.6
86.6
N.A.
0
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
0
6.6
P-Site Similarity:
100
100
13.3
86.6
N.A.
86.6
86.6
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
13.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
10
0
0
10
0
0
30
0
10
0
0
0
% A
% Cys:
0
0
0
0
10
0
0
0
0
0
0
50
0
0
0
% C
% Asp:
0
10
20
0
0
0
0
10
0
0
10
0
10
0
0
% D
% Glu:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
50
20
0
0
0
0
10
0
0
10
10
10
0
% F
% Gly:
20
0
0
0
10
0
10
10
0
0
0
10
0
10
0
% G
% His:
0
0
0
0
0
0
10
10
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
50
0
0
0
0
30
10
50
0
0
10
0
% I
% Lys:
0
0
0
0
0
0
0
0
10
10
0
10
0
0
10
% K
% Leu:
10
0
0
0
0
10
0
0
0
0
0
0
20
0
0
% L
% Met:
0
0
0
0
10
0
0
0
0
10
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% N
% Pro:
0
10
10
0
0
10
50
10
0
10
0
0
50
0
50
% P
% Gln:
0
0
0
0
10
20
0
0
0
0
0
0
0
0
10
% Q
% Arg:
0
50
10
0
50
60
0
10
0
0
10
0
0
0
0
% R
% Ser:
40
10
10
0
0
0
10
50
10
10
0
0
0
60
20
% S
% Thr:
20
0
0
10
0
0
0
0
40
20
20
10
10
0
10
% T
% Val:
0
10
0
10
0
0
0
0
0
0
10
0
0
10
0
% V
% Trp:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _