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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SERF1A All Species: 0.61
Human Site: Y80 Identified Species: 2.22
UniProt: O75920 Number Species: 6
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75920 NP_075267.1 110 12349 Y80 G S R Y Y L A Y G S I T P I S
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001109623 170 18297 P115 A S C P T L L P F A C V P G A
Dog Lupus familis XP_860249 170 18362 P115 A S C P T L L P F A C V P G A
Cat Felis silvestris
Mouse Mus musculus O88892 62 7304 A33 R K E D S L T A S Q R K Q R D
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001231983 62 7152 A33 R K E D S L S A S Q R K Q R D
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VEW2 60 6866 T31 G K R T D N L T V E Q R K A R
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q3E7B7 68 7931 A39 K K R M E S D A E I L R Q K Q
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 30 30 N.A. 40 N.A. N.A. N.A. 38.1 N.A. N.A. N.A. 27.2 N.A. N.A. N.A.
Protein Similarity: 100 N.A. 39.4 39.4 N.A. 46.3 N.A. N.A. N.A. 41.8 N.A. N.A. N.A. 38.1 N.A. N.A. N.A.
P-Site Identity: 100 N.A. 20 20 N.A. 6.6 N.A. N.A. N.A. 6.6 N.A. N.A. N.A. 13.3 N.A. N.A. N.A.
P-Site Similarity: 100 N.A. 33.3 33.3 N.A. 6.6 N.A. N.A. N.A. 13.3 N.A. N.A. N.A. 13.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 27.2 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 37.2 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 29 0 0 0 0 0 15 43 0 29 0 0 0 15 29 % A
% Cys: 0 0 29 0 0 0 0 0 0 0 29 0 0 0 0 % C
% Asp: 0 0 0 29 15 0 15 0 0 0 0 0 0 0 29 % D
% Glu: 0 0 29 0 15 0 0 0 15 15 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 29 0 0 0 0 0 0 % F
% Gly: 29 0 0 0 0 0 0 0 15 0 0 0 0 29 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 15 15 0 0 15 0 % I
% Lys: 15 58 0 0 0 0 0 0 0 0 0 29 15 15 0 % K
% Leu: 0 0 0 0 0 72 43 0 0 0 15 0 0 0 0 % L
% Met: 0 0 0 15 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 15 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 29 0 0 0 29 0 0 0 0 43 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 29 15 0 43 0 15 % Q
% Arg: 29 0 43 0 0 0 0 0 0 0 29 29 0 29 15 % R
% Ser: 0 43 0 0 29 15 15 0 29 15 0 0 0 0 15 % S
% Thr: 0 0 0 15 29 0 15 15 0 0 0 15 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 15 0 0 29 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 15 15 0 0 15 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _