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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DYSF
All Species:
4.24
Human Site:
Y741
Identified Species:
18.67
UniProt:
O75923
Number Species:
5
Phosphosite Substitution
Charge Score:
0.4
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75923
NP_001123927.1
2080
237295
Y741
T
H
L
D
Q
Y
L
Y
Q
L
R
T
H
H
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_540237
2083
237082
Y744
T
H
L
D
R
H
L
Y
R
L
R
T
R
H
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9ESD7
2090
237892
L751
T
H
L
D
Q
Y
L
L
R
L
R
T
R
H
L
Rat
Rattus norvegicus
Q9ERC5
1993
226321
G691
Q
N
S
S
D
D
E
G
D
E
A
G
D
L
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q5SPC5
1992
226210
D687
S
E
E
E
A
E
D
D
G
D
L
T
S
V
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q17388
2034
235223
D755
G
L
A
L
K
W
K
D
E
A
D
I
Y
D
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
93.4
N.A.
93.3
30
N.A.
N.A.
N.A.
N.A.
29.5
N.A.
N.A.
N.A.
26.2
N.A.
Protein Similarity:
100
N.A.
N.A.
97
N.A.
96.5
48.5
N.A.
N.A.
N.A.
N.A.
48.6
N.A.
N.A.
N.A.
45.9
N.A.
P-Site Identity:
100
N.A.
N.A.
73.3
N.A.
80
0
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
N.A.
N.A.
93.3
N.A.
86.6
6.6
N.A.
N.A.
N.A.
N.A.
20
N.A.
N.A.
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
17
0
17
0
0
0
0
17
17
0
0
0
17
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
50
17
17
17
34
17
17
17
0
17
17
0
% D
% Glu:
0
17
17
17
0
17
17
0
17
17
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
17
0
0
0
0
0
0
17
17
0
0
17
0
0
17
% G
% His:
0
50
0
0
0
17
0
0
0
0
0
0
17
50
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
17
0
0
0
% I
% Lys:
0
0
0
0
17
0
17
0
0
0
0
0
0
0
0
% K
% Leu:
0
17
50
17
0
0
50
17
0
50
17
0
0
17
50
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
17
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
17
% P
% Gln:
17
0
0
0
34
0
0
0
17
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
17
0
0
0
34
0
50
0
34
0
0
% R
% Ser:
17
0
17
17
0
0
0
0
0
0
0
0
17
0
0
% S
% Thr:
50
0
0
0
0
0
0
0
0
0
0
67
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
17
0
% V
% Trp:
0
0
0
0
0
17
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
34
0
34
0
0
0
0
17
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _