KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIAS1
All Species:
21.52
Human Site:
T291
Identified Species:
47.33
UniProt:
O75925
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75925
NP_057250.1
651
71836
T291
L
V
K
Q
L
S
S
T
V
L
L
Q
R
L
R
Chimpanzee
Pan troglodytes
XP_523109
766
83908
T406
L
V
K
Q
L
S
S
T
V
L
L
Q
R
L
R
Rhesus Macaque
Macaca mulatta
XP_001082800
642
70843
L285
Q
L
S
S
T
V
L
L
Q
R
L
R
A
K
G
Dog
Lupus familis
XP_535524
651
71773
T291
L
V
K
Q
L
S
S
T
V
L
L
Q
R
L
R
Cat
Felis silvestris
Mouse
Mus musculus
O88907
651
71599
T291
L
V
K
Q
L
S
S
T
V
L
L
Q
R
L
R
Rat
Rattus norvegicus
O70260
628
68345
S271
S
E
F
G
R
N
Y
S
L
S
V
Y
L
V
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516107
756
82793
T390
L
V
K
Q
L
S
S
T
V
L
L
Q
R
L
R
Chicken
Gallus gallus
NP_001026627
564
62782
T207
L
R
F
C
L
S
E
T
S
C
P
Q
E
D
H
Frog
Xenopus laevis
NP_001079161
649
71676
A290
L
V
K
Q
L
S
S
A
I
L
L
Q
R
L
R
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q94361
793
89556
L385
H
R
V
N
S
D
I
L
F
K
R
L
N
Q
N
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q680Q4
884
97015
G319
L
N
L
I
P
E
E
G
K
G
E
T
F
E
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
84.9
98.6
99.6
N.A.
98
58.6
N.A.
82.2
82.9
87
N.A.
N.A.
N.A.
N.A.
24
N.A.
Protein Similarity:
100
84.9
98.6
99.8
N.A.
98.7
72
N.A.
84.2
85
94.3
N.A.
N.A.
N.A.
N.A.
40.9
N.A.
P-Site Identity:
100
100
6.6
100
N.A.
100
6.6
N.A.
100
33.3
86.6
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
100
20
100
N.A.
100
40
N.A.
100
33.3
93.3
N.A.
N.A.
N.A.
N.A.
0
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
10
0
0
0
0
10
0
0
% A
% Cys:
0
0
0
10
0
0
0
0
0
10
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
10
0
0
0
0
0
0
0
10
10
% D
% Glu:
0
10
0
0
0
10
19
0
0
0
10
0
10
10
0
% E
% Phe:
0
0
19
0
0
0
0
0
10
0
0
0
10
0
0
% F
% Gly:
0
0
0
10
0
0
0
10
0
10
0
0
0
0
10
% G
% His:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% H
% Ile:
0
0
0
10
0
0
10
0
10
0
0
0
0
0
0
% I
% Lys:
0
0
55
0
0
0
0
0
10
10
0
0
0
10
0
% K
% Leu:
73
10
10
0
64
0
10
19
10
55
64
10
10
55
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
10
0
10
0
0
0
0
0
0
10
0
10
% N
% Pro:
0
0
0
0
10
0
0
0
0
0
10
0
0
0
0
% P
% Gln:
10
0
0
55
0
0
0
0
10
0
0
64
0
10
0
% Q
% Arg:
0
19
0
0
10
0
0
0
0
10
10
10
55
0
64
% R
% Ser:
10
0
10
10
10
64
55
10
10
10
0
0
0
0
0
% S
% Thr:
0
0
0
0
10
0
0
55
0
0
0
10
0
0
0
% T
% Val:
0
55
10
0
0
10
0
0
46
0
10
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
0
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _