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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIAS1
All Species:
22.73
Human Site:
Y25
Identified Species:
50
UniProt:
O75925
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75925
NP_057250.1
651
71836
Y25
E
L
Q
V
L
L
G
Y
A
G
R
N
K
H
G
Chimpanzee
Pan troglodytes
XP_523109
766
83908
Y140
E
L
Q
V
L
L
G
Y
A
G
R
N
K
H
G
Rhesus Macaque
Macaca mulatta
XP_001082800
642
70843
G23
Y
A
G
R
N
K
H
G
R
K
H
E
L
L
T
Dog
Lupus familis
XP_535524
651
71773
Y25
E
L
Q
V
L
L
G
Y
A
G
R
N
K
H
G
Cat
Felis silvestris
Mouse
Mus musculus
O88907
651
71599
Y25
E
L
Q
V
L
L
G
Y
A
G
R
N
K
H
G
Rat
Rattus norvegicus
O70260
628
68345
H9
A
E
L
G
E
L
K
H
M
V
M
S
F
R
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516107
756
82793
Y124
E
L
Q
V
L
L
G
Y
A
G
R
N
K
H
G
Chicken
Gallus gallus
NP_001026627
564
62782
Frog
Xenopus laevis
NP_001079161
649
71676
Y25
E
L
Q
V
L
L
G
Y
A
G
R
N
K
H
G
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q94361
793
89556
Q36
K
L
R
V
H
D
L
Q
S
I
I
S
Q
L
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q680Q4
884
97015
Q25
E
L
K
D
V
L
T
Q
L
G
L
S
K
Q
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
84.9
98.6
99.6
N.A.
98
58.6
N.A.
82.2
82.9
87
N.A.
N.A.
N.A.
N.A.
24
N.A.
Protein Similarity:
100
84.9
98.6
99.8
N.A.
98.7
72
N.A.
84.2
85
94.3
N.A.
N.A.
N.A.
N.A.
40.9
N.A.
P-Site Identity:
100
100
0
100
N.A.
100
6.6
N.A.
100
0
100
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
100
100
0
100
N.A.
100
20
N.A.
100
0
100
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
60
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
0
0
0
0
0
55
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
10
0
0
0
0
0
0
0
0
0
% D
% Glu:
64
10
0
0
10
0
0
0
0
0
0
10
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% F
% Gly:
0
0
10
10
0
0
55
10
0
64
0
0
0
0
64
% G
% His:
0
0
0
0
10
0
10
10
0
0
10
0
0
55
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
10
10
0
0
0
0
% I
% Lys:
10
0
10
0
0
10
10
0
0
10
0
0
64
0
0
% K
% Leu:
0
73
10
0
55
73
10
0
10
0
10
0
10
19
0
% L
% Met:
0
0
0
0
0
0
0
0
10
0
10
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
0
0
0
0
0
55
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
55
0
0
0
0
19
0
0
0
0
10
10
0
% Q
% Arg:
0
0
10
10
0
0
0
0
10
0
55
0
0
10
0
% R
% Ser:
0
0
0
0
0
0
0
0
10
0
0
28
0
0
10
% S
% Thr:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
10
% T
% Val:
0
0
0
64
10
0
0
0
0
10
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
55
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _