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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIAS2
All Species:
29.39
Human Site:
S494
Identified Species:
53.89
UniProt:
O75928
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75928
NP_004662.2
621
68240
S494
K
R
K
C
I
F
M
S
E
T
Q
S
S
P
T
Chimpanzee
Pan troglodytes
XP_001147441
612
67116
S485
K
R
K
C
I
F
M
S
E
T
Q
S
S
P
T
Rhesus Macaque
Macaca mulatta
XP_001085703
612
67146
S485
K
R
K
C
I
F
M
S
E
T
Q
S
S
P
T
Dog
Lupus familis
XP_852829
541
60303
S415
Q
P
C
T
K
I
E
S
S
S
V
L
S
K
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8C5D8
621
68407
S494
K
R
K
C
I
F
M
S
E
T
Q
S
S
P
T
Rat
Rattus norvegicus
Q6AZ28
572
63413
S446
Q
P
C
T
K
V
E
S
S
S
V
F
S
K
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506015
622
68325
S494
K
R
K
C
I
F
M
S
E
T
Q
G
S
P
T
Chicken
Gallus gallus
NP_001025797
622
68442
S494
K
R
K
C
I
F
M
S
E
T
Q
G
S
P
T
Frog
Xenopus laevis
NP_001084972
584
64427
E457
S
K
I
C
S
A
I
E
G
G
E
T
T
R
K
Zebra Danio
Brachydanio rerio
XP_685704
623
69106
S494
K
K
R
C
I
Y
M
S
K
A
E
E
M
H
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q94361
793
89556
A590
P
G
R
H
T
A
S
A
E
L
A
A
Q
K
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q680Q4
884
97015
A717
I
N
G
G
Y
T
M
A
P
E
T
S
M
A
S
Baker's Yeast
Sacchar. cerevisiae
Q12216
726
81160
T556
A
T
T
N
I
N
D
T
P
T
N
N
S
S
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
98.3
84
N.A.
98
87.5
N.A.
93.8
92.4
74.7
71.5
N.A.
N.A.
N.A.
23.4
N.A.
Protein Similarity:
100
98.5
98.3
85.6
N.A.
99
90
N.A.
97.1
95.8
84.2
83.3
N.A.
N.A.
N.A.
39.8
N.A.
P-Site Identity:
100
100
100
13.3
N.A.
100
13.3
N.A.
93.3
93.3
6.6
33.3
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
100
100
100
26.6
N.A.
100
26.6
N.A.
93.3
93.3
40
73.3
N.A.
N.A.
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.3
20.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
34.8
38.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
16
0
16
0
8
8
8
0
8
0
% A
% Cys:
0
0
16
62
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
16
8
54
8
16
8
0
0
0
% E
% Phe:
0
0
0
0
0
47
0
0
0
0
0
8
0
0
0
% F
% Gly:
0
8
8
8
0
0
0
0
8
8
0
16
0
0
0
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
8
0
8
0
62
8
8
0
0
0
0
0
0
0
8
% I
% Lys:
54
16
47
0
16
0
0
0
8
0
0
0
0
24
8
% K
% Leu:
0
0
0
0
0
0
0
0
0
8
0
8
0
0
0
% L
% Met:
0
0
0
0
0
0
62
0
0
0
0
0
16
0
0
% M
% Asn:
0
8
0
8
0
8
0
0
0
0
8
8
0
0
0
% N
% Pro:
8
16
0
0
0
0
0
0
16
0
0
0
0
47
16
% P
% Gln:
16
0
0
0
0
0
0
0
0
0
47
0
8
0
0
% Q
% Arg:
0
47
16
0
0
0
0
0
0
0
0
0
0
8
0
% R
% Ser:
8
0
0
0
8
0
8
70
16
16
0
39
70
8
16
% S
% Thr:
0
8
8
16
8
8
0
8
0
54
8
8
8
0
54
% T
% Val:
0
0
0
0
0
8
0
0
0
0
16
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
8
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _