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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIAS2
All Species:
22.12
Human Site:
T457
Identified Species:
40.56
UniProt:
O75928
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75928
NP_004662.2
621
68240
T457
L
S
K
P
C
S
V
T
V
A
S
E
A
S
K
Chimpanzee
Pan troglodytes
XP_001147441
612
67116
T448
L
S
K
P
C
S
V
T
V
A
S
E
A
S
K
Rhesus Macaque
Macaca mulatta
XP_001085703
612
67146
T448
L
S
K
P
C
S
V
T
V
A
S
E
A
S
K
Dog
Lupus familis
XP_852829
541
60303
C379
F
M
E
I
L
N
D
C
S
D
V
D
E
I
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8C5D8
621
68407
T457
F
S
K
P
C
S
V
T
V
A
S
D
A
S
K
Rat
Rattus norvegicus
Q6AZ28
572
63413
C410
F
M
E
I
L
N
D
C
S
D
V
D
E
I
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506015
622
68325
A457
L
S
K
P
C
S
V
A
V
A
T
E
A
S
K
Chicken
Gallus gallus
NP_001025797
622
68442
T457
V
S
K
P
C
S
V
T
V
A
N
E
V
N
K
Frog
Xenopus laevis
NP_001084972
584
64427
G421
E
I
K
F
Q
Q
D
G
S
W
C
P
M
R
P
Zebra Danio
Brachydanio rerio
XP_685704
623
69106
S456
V
R
Q
S
A
V
V
S
V
P
E
T
S
S
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q94361
793
89556
T539
G
T
A
S
C
S
S
T
N
G
N
G
L
A
N
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q680Q4
884
97015
S474
P
D
G
S
L
C
P
S
A
V
D
I
K
R
K
Baker's Yeast
Sacchar. cerevisiae
Q12216
726
81160
Q449
Q
G
T
V
K
Q
E
Q
D
Y
D
S
R
N
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
98.3
84
N.A.
98
87.5
N.A.
93.8
92.4
74.7
71.5
N.A.
N.A.
N.A.
23.4
N.A.
Protein Similarity:
100
98.5
98.3
85.6
N.A.
99
90
N.A.
97.1
95.8
84.2
83.3
N.A.
N.A.
N.A.
39.8
N.A.
P-Site Identity:
100
100
100
6.6
N.A.
86.6
6.6
N.A.
86.6
73.3
6.6
20
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
100
100
100
26.6
N.A.
93.3
26.6
N.A.
93.3
93.3
6.6
46.6
N.A.
N.A.
N.A.
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.3
20.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
34.8
38.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
8
0
0
8
8
47
0
0
39
8
8
% A
% Cys:
0
0
0
0
54
8
0
16
0
0
8
0
0
0
0
% C
% Asp:
0
8
0
0
0
0
24
0
8
16
16
24
0
0
0
% D
% Glu:
8
0
16
0
0
0
8
0
0
0
8
39
16
0
0
% E
% Phe:
24
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
8
8
0
0
0
0
8
0
8
0
8
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
16
0
0
0
0
0
0
0
8
0
16
0
% I
% Lys:
0
0
54
0
8
0
0
0
0
0
0
0
8
0
70
% K
% Leu:
31
0
0
0
24
0
0
0
0
0
0
0
8
0
0
% L
% Met:
0
16
0
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
0
0
0
16
0
0
8
0
16
0
0
16
8
% N
% Pro:
8
0
0
47
0
0
8
0
0
8
0
8
0
0
8
% P
% Gln:
8
0
8
0
8
16
0
8
0
0
0
0
0
0
0
% Q
% Arg:
0
8
0
0
0
0
0
0
0
0
0
0
8
16
0
% R
% Ser:
0
47
0
24
0
54
8
16
24
0
31
8
8
47
0
% S
% Thr:
0
8
8
0
0
0
0
47
0
0
8
8
0
0
8
% T
% Val:
16
0
0
8
0
8
54
0
54
8
16
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _