KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIAS2
All Species:
31.21
Human Site:
Y373
Identified Species:
57.22
UniProt:
O75928
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75928
NP_004662.2
621
68240
Y373
Q
C
F
D
A
A
L
Y
L
Q
M
N
E
K
K
Chimpanzee
Pan troglodytes
XP_001147441
612
67116
Y364
Q
C
F
D
A
A
L
Y
L
Q
M
N
E
K
K
Rhesus Macaque
Macaca mulatta
XP_001085703
612
67146
Y364
Q
C
F
D
A
A
L
Y
L
Q
M
N
E
K
K
Dog
Lupus familis
XP_852829
541
60303
K295
S
R
A
L
I
K
E
K
L
T
A
D
P
D
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8C5D8
621
68407
Y373
Q
C
F
D
A
A
L
Y
L
Q
M
N
E
K
K
Rat
Rattus norvegicus
Q6AZ28
572
63413
K326
S
R
A
L
I
K
E
K
L
T
A
D
P
D
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506015
622
68325
Y373
Q
C
F
D
A
A
L
Y
L
Q
M
N
E
K
K
Chicken
Gallus gallus
NP_001025797
622
68442
Y373
Q
C
F
D
A
A
L
Y
L
Q
M
N
E
K
K
Frog
Xenopus laevis
NP_001084972
584
64427
T337
P
D
S
E
I
A
T
T
S
L
R
V
S
L
M
Zebra Danio
Brachydanio rerio
XP_685704
623
69106
Y372
Q
C
F
D
A
A
L
Y
L
Q
M
N
E
K
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q94361
793
89556
Y455
Q
C
F
D
L
L
S
Y
L
M
M
N
E
K
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q680Q4
884
97015
F390
G
C
F
D
L
D
V
F
V
E
L
N
Q
R
S
Baker's Yeast
Sacchar. cerevisiae
Q12216
726
81160
F365
Q
C
F
D
A
L
W
F
L
H
S
Q
S
Q
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
98.3
84
N.A.
98
87.5
N.A.
93.8
92.4
74.7
71.5
N.A.
N.A.
N.A.
23.4
N.A.
Protein Similarity:
100
98.5
98.3
85.6
N.A.
99
90
N.A.
97.1
95.8
84.2
83.3
N.A.
N.A.
N.A.
39.8
N.A.
P-Site Identity:
100
100
100
6.6
N.A.
100
6.6
N.A.
100
100
6.6
100
N.A.
N.A.
N.A.
73.3
N.A.
P-Site Similarity:
100
100
100
13.3
N.A.
100
13.3
N.A.
100
100
13.3
100
N.A.
N.A.
N.A.
73.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.3
20.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
34.8
38.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
40
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
73.3
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
16
0
62
62
0
0
0
0
16
0
0
0
0
% A
% Cys:
0
77
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
77
0
8
0
0
0
0
0
16
0
16
0
% D
% Glu:
0
0
0
8
0
0
16
0
0
8
0
0
62
0
0
% E
% Phe:
0
0
77
0
0
0
0
16
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
0
0
24
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
16
0
16
0
0
0
0
0
62
62
% K
% Leu:
0
0
0
16
16
16
54
0
85
8
8
0
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
8
62
0
0
0
8
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
70
0
0
0
% N
% Pro:
8
0
0
0
0
0
0
0
0
0
0
0
16
0
0
% P
% Gln:
70
0
0
0
0
0
0
0
0
54
0
8
8
8
0
% Q
% Arg:
0
16
0
0
0
0
0
0
0
0
8
0
0
8
0
% R
% Ser:
16
0
8
0
0
0
8
0
8
0
8
0
16
0
24
% S
% Thr:
0
0
0
0
0
0
8
8
0
16
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
8
0
8
0
0
8
0
0
8
% V
% Trp:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
62
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _