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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMNDC1
All Species:
29.09
Human Site:
S24
Identified Species:
53.33
UniProt:
O75940
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75940
NP_005862.1
238
26711
S24
Q
Q
V
E
A
A
L
S
G
N
G
E
N
E
D
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_864410
199
22437
P15
K
D
L
L
S
T
Q
P
S
E
T
L
A
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGT7
238
26735
S24
Q
Q
V
E
A
A
L
S
G
N
G
E
N
E
D
Rat
Rattus norvegicus
Q4QQU6
238
26765
S24
Q
Q
V
E
A
A
L
S
G
N
G
E
N
E
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512808
309
34597
S95
Q
Q
V
E
A
A
L
S
G
N
G
E
N
E
D
Chicken
Gallus gallus
XP_421753
238
26635
S24
Q
Q
V
E
A
A
L
S
G
N
A
D
N
E
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q7ZV80
237
26922
S24
Q
Q
V
E
A
A
L
S
I
D
P
D
N
E
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001138001
243
28185
R43
D
E
V
I
T
L
T
R
D
L
I
Q
T
Q
L
Honey Bee
Apis mellifera
XP_393514
235
26699
K29
P
S
N
E
E
L
L
K
L
K
I
D
L
E
E
Nematode Worm
Caenorhab. elegans
NP_001022932
239
26048
T24
A
A
L
L
G
D
P
T
N
V
E
L
L
K
L
Sea Urchin
Strong. purpuratus
XP_782685
238
26660
T27
Q
Q
V
E
A
A
L
T
N
D
P
E
N
E
E
Poplar Tree
Populus trichocarpa
XP_002328804
287
32224
V30
H
Q
V
R
Q
L
L
V
D
D
P
G
N
S
E
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_178361
300
33452
S32
E
Q
V
R
Q
L
L
S
E
D
P
R
N
S
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
83.1
N.A.
99.5
99.1
N.A.
75.7
95.8
N.A.
78.1
N.A.
45.6
47.9
33.8
49.5
Protein Similarity:
100
N.A.
N.A.
83.6
N.A.
99.5
99.1
N.A.
76
97.9
N.A.
86.9
N.A.
58.4
64.2
51
67.6
P-Site Identity:
100
N.A.
N.A.
0
N.A.
100
100
N.A.
100
86.6
N.A.
73.3
N.A.
6.6
20
0
66.6
P-Site Similarity:
100
N.A.
N.A.
20
N.A.
100
100
N.A.
100
93.3
N.A.
86.6
N.A.
26.6
33.3
20
86.6
Percent
Protein Identity:
33.4
N.A.
N.A.
28.3
N.A.
N.A.
Protein Similarity:
50.8
N.A.
N.A.
44.3
N.A.
N.A.
P-Site Identity:
26.6
N.A.
N.A.
33.3
N.A.
N.A.
P-Site Similarity:
40
N.A.
N.A.
53.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
54
54
0
0
0
0
8
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
0
0
0
8
0
0
16
31
0
24
0
0
47
% D
% Glu:
8
8
0
62
8
0
0
0
8
8
8
39
0
62
31
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
8
0
0
0
39
0
31
8
0
0
0
% G
% His:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
0
0
8
0
16
0
0
0
0
% I
% Lys:
8
0
0
0
0
0
0
8
0
8
0
0
0
8
0
% K
% Leu:
0
0
16
16
0
31
77
0
8
8
0
16
16
0
16
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
0
0
0
16
39
0
0
70
0
0
% N
% Pro:
8
0
0
0
0
0
8
8
0
0
31
0
0
0
0
% P
% Gln:
54
70
0
0
16
0
8
0
0
0
0
8
0
8
0
% Q
% Arg:
0
0
0
16
0
0
0
8
0
0
0
8
0
0
0
% R
% Ser:
0
8
0
0
8
0
0
54
8
0
0
0
0
24
8
% S
% Thr:
0
0
0
0
8
8
8
16
0
0
8
0
8
0
0
% T
% Val:
0
0
77
0
0
0
0
8
0
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _