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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMNDC1
All Species:
25.45
Human Site:
S51
Identified Species:
46.67
UniProt:
O75940
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75940
NP_005862.1
238
26711
S51
E
L
T
K
D
L
L
S
T
Q
P
S
E
T
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_864410
199
22437
K35
T
Q
P
T
H
S
W
K
V
G
D
K
C
M
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGT7
238
26735
S51
E
L
T
K
D
L
L
S
T
Q
P
S
E
T
L
Rat
Rattus norvegicus
Q4QQU6
238
26765
S51
E
L
T
K
D
L
L
S
T
Q
P
S
E
T
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512808
309
34597
S122
E
L
T
K
D
L
L
S
T
Q
P
S
E
T
L
Chicken
Gallus gallus
XP_421753
238
26635
S51
E
L
T
K
D
L
L
S
T
Q
P
S
E
T
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q7ZV80
237
26922
T51
E
L
T
K
D
L
L
T
S
Q
P
A
E
G
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001138001
243
28185
N70
S
T
K
R
D
S
S
N
Y
F
D
E
I
E
A
Honey Bee
Apis mellifera
XP_393514
235
26699
E51
L
I
K
S
Q
Q
Q
E
K
R
Q
A
N
G
M
Nematode Worm
Caenorhab. elegans
NP_001022932
239
26048
D44
E
I
I
S
L
Q
E
D
L
A
E
T
D
K
A
Sea Urchin
Strong. purpuratus
XP_782685
238
26660
S55
L
T
S
D
L
L
R
S
S
Q
G
A
S
T
S
Poplar Tree
Populus trichocarpa
XP_002328804
287
32224
S67
K
Q
N
E
I
S
G
S
H
L
G
T
G
A
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_178361
300
33452
A59
A
L
T
E
E
V
L
A
T
A
K
Q
N
E
I
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
83.1
N.A.
99.5
99.1
N.A.
75.7
95.8
N.A.
78.1
N.A.
45.6
47.9
33.8
49.5
Protein Similarity:
100
N.A.
N.A.
83.6
N.A.
99.5
99.1
N.A.
76
97.9
N.A.
86.9
N.A.
58.4
64.2
51
67.6
P-Site Identity:
100
N.A.
N.A.
0
N.A.
100
100
N.A.
100
100
N.A.
66.6
N.A.
6.6
0
6.6
26.6
P-Site Similarity:
100
N.A.
N.A.
0
N.A.
100
100
N.A.
100
100
N.A.
86.6
N.A.
20
26.6
26.6
46.6
Percent
Protein Identity:
33.4
N.A.
N.A.
28.3
N.A.
N.A.
Protein Similarity:
50.8
N.A.
N.A.
44.3
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
26.6
N.A.
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
60
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
0
8
0
16
0
24
0
8
24
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
0
0
8
54
0
0
8
0
0
16
0
8
0
0
% D
% Glu:
54
0
0
16
8
0
8
8
0
0
8
8
47
16
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
8
0
0
8
16
0
8
16
0
% G
% His:
0
0
0
0
8
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
0
16
8
0
8
0
0
0
0
0
0
0
8
0
8
% I
% Lys:
8
0
16
47
0
0
0
8
8
0
8
8
0
8
0
% K
% Leu:
16
54
0
0
16
54
54
0
8
8
0
0
0
0
39
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% M
% Asn:
0
0
8
0
0
0
0
8
0
0
0
0
16
0
0
% N
% Pro:
0
0
8
0
0
0
0
0
0
0
47
0
0
0
0
% P
% Gln:
0
16
0
0
8
16
8
0
0
54
8
8
0
0
0
% Q
% Arg:
0
0
0
8
0
0
8
0
0
8
0
0
0
0
0
% R
% Ser:
8
0
8
16
0
24
8
54
16
0
0
39
8
0
16
% S
% Thr:
8
16
54
8
0
0
0
8
47
0
0
16
0
47
8
% T
% Val:
0
0
0
0
0
8
0
0
8
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _