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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMNDC1
All Species:
20.91
Human Site:
S66
Identified Species:
38.33
UniProt:
O75940
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75940
NP_005862.1
238
26711
S66
A
S
S
D
S
F
A
S
T
Q
P
T
H
S
W
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_864410
199
22437
C50
I
W
S
E
D
G
Q
C
Y
E
A
E
I
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGT7
238
26735
S66
A
S
S
D
S
F
A
S
T
Q
P
T
H
S
W
Rat
Rattus norvegicus
Q4QQU6
238
26765
S66
T
S
S
D
S
F
A
S
T
Q
P
T
H
S
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512808
309
34597
S137
T
S
S
D
S
S
A
S
A
Q
P
S
H
S
W
Chicken
Gallus gallus
XP_421753
238
26635
S66
A
S
S
D
S
S
A
S
A
L
P
S
H
S
W
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q7ZV80
237
26922
T66
T
S
T
K
S
S
E
T
V
A
P
S
H
S
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001138001
243
28185
L85
A
L
L
E
A
E
K
L
V
S
A
A
K
I
W
Honey Bee
Apis mellifera
XP_393514
235
26699
L66
D
A
K
D
P
I
L
L
A
V
L
A
N
K
W
Nematode Worm
Caenorhab. elegans
NP_001022932
239
26048
V59
E
S
S
E
R
A
V
V
A
P
Q
V
I
H
K
Sea Urchin
Strong. purpuratus
XP_782685
238
26660
V70
A
E
P
D
A
E
D
V
P
V
V
T
H
P
W
Poplar Tree
Populus trichocarpa
XP_002328804
287
32224
P82
A
S
P
G
Y
A
E
P
Q
E
A
D
Q
H
E
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_178361
300
33452
S74
S
L
S
D
A
G
V
S
A
E
A
T
P
G
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
83.1
N.A.
99.5
99.1
N.A.
75.7
95.8
N.A.
78.1
N.A.
45.6
47.9
33.8
49.5
Protein Similarity:
100
N.A.
N.A.
83.6
N.A.
99.5
99.1
N.A.
76
97.9
N.A.
86.9
N.A.
58.4
64.2
51
67.6
P-Site Identity:
100
N.A.
N.A.
6.6
N.A.
100
93.3
N.A.
73.3
73.3
N.A.
40
N.A.
13.3
13.3
13.3
33.3
P-Site Similarity:
100
N.A.
N.A.
20
N.A.
100
93.3
N.A.
80
80
N.A.
60
N.A.
26.6
26.6
20
40
Percent
Protein Identity:
33.4
N.A.
N.A.
28.3
N.A.
N.A.
Protein Similarity:
50.8
N.A.
N.A.
44.3
N.A.
N.A.
P-Site Identity:
13.3
N.A.
N.A.
26.6
N.A.
N.A.
P-Site Similarity:
20
N.A.
N.A.
46.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
47
8
0
0
24
16
39
0
39
8
31
16
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
62
8
0
8
0
0
0
0
8
0
0
0
% D
% Glu:
8
8
0
24
0
16
16
0
0
24
0
8
0
8
16
% E
% Phe:
0
0
0
0
0
24
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
8
0
16
0
0
0
0
0
0
0
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
54
16
0
% H
% Ile:
8
0
0
0
0
8
0
0
0
0
0
0
16
8
0
% I
% Lys:
0
0
8
8
0
0
8
0
0
0
0
0
8
8
8
% K
% Leu:
0
16
8
0
0
0
8
16
0
8
8
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% N
% Pro:
0
0
16
0
8
0
0
8
8
8
47
0
8
8
0
% P
% Gln:
0
0
0
0
0
0
8
0
8
31
8
0
8
0
0
% Q
% Arg:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
8
62
62
0
47
24
0
47
0
8
0
24
0
47
8
% S
% Thr:
24
0
8
0
0
0
0
8
24
0
0
39
0
0
0
% T
% Val:
0
0
0
0
0
0
16
16
16
16
8
8
0
0
0
% V
% Trp:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
70
% W
% Tyr:
0
0
0
0
8
0
0
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _